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Genome Technology Program
- Overview
- Related Information
- Reports
- Policies
- Funding Opportunities
- Advanced Sequencing Technology Awards
- Publications and Patents
- Staff
Genome Technology Program Overview
The Genome Technology program supports research to develop new methods, technologies and instruments that enable rapid, low-cost determination of DNA sequence, SNP genotyping (Genetic Variation Program) and functional genomics (broadly defined) experiments (Functional Analysis Program). Priorities include the refinement of current technologies to increase efficiency and decrease cost while maintaining or improving data quality, and the development of completely novel approaches to achieve orders-of-magnitude improvement. Integration of process steps is key to achieving these goals.
The program also supports and coordinates transfer of technology from developers to users, and promotes collaborative, multidisciplinary programs that closely integrate research projects at academic and industrial laboratories.
The involvement of The National Human Genome Research Institute (NHGRI) in BECON [becon.nih.gov], the trans-National Institutes of Health (NIH) Bioengineering Consortium, is through the Genome Technology program. The development of integrated concepts and tools for genomic research benefits from bioengineering research and methods. NHGRI supports bioengineering research through grants made in response to NHGRI program announcements and requests for application, and through NHGRI participation in BECON's bioengineering funding [becon.nih.gov] opportunities, such as the Bioengineering Research Grants (BRG) and Bioengineering Research Partnerships (BRP) programs.
Genome Technology Program Related Information
Genome Technology Program Reports
- Sequencing and Re-Sequencing the Biome! July 2002
- Sequencing Technology Workshop May 13, 1998
- Sequencing Variation Workshop March 31-April 1, 1997
- Functional Analysis Workshop December 2-3, 1997
Genome Technology Program Policies
- Principles and Guidelines for Recipients of NIH Research Grants and Contracts on Obtaining and Disseminating Biomedical Research Resources: Final Notice [ott.od.nih.gov]
Genome Technology Program Funding Opportunities
Requests for Applications (RFAs)
RFA-RM-10-007: [grants.gov] Production Of Human Proteins To Be Used For Generating Affinity Reagents (U01)
Program Announcements
PA-10-010 [grants.nih.gov]: Exploratory/Developmental (R21) Bioengineering Research Grants (EBRG)
PA-10-009 [grants.nih.gov]: Bioengineering Research Grants (BRG [R01])
PA-09-267 [grants.nih.gov]: Bioengineering Nanotechnology Initiative (SBIR [R43/44])
PA-09-266 [grants.nih.gov]: Bioengineering Nanotechnology Initiative (STTR [R41/R42])
PA-08-053 [grants.nih.gov]: Nanoscience and Nanotechnology in Biology and Medicine (R21)
PA-08-052 [grants.nih.gov]: Nanoscience and Nanotechnology in Biology and Medicine (R01)
PAR-08-010 [grants.nih.gov]: Continued Development and Maintenance of Software (R01)
PA-07-459 [grants.nih.gov]: Feasibility Studies to Develop Technology and Methods for Genomics, Population Genomics and ELSI (R21)
PA-07-458 [grants.nih.gov]: Technology and Methods Development for Genomics, Population Genomics and ELSI (R01)
PAR-07-352 [grants.nih.gov]: Bioengineering Research Partnerships (BRP) [R01]
Centers of Excellence in Genomic Science (CEGS)
Small Business Funding Opportunities [grants.nih.gov]: Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) program information.
Genome Technology Program Advanced Sequencing Technology Awards
In 2004, NHGRI initiated a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.
- Advanced Sequencing Technology Awards 2009
- NHGRI Uses Recovery Act Funds to Accelerate
Genome Research to Improve Human Health
October 8, 2009 Online News Feature - Advanced Sequencing Technology Awards 2008
-
NHGRI Seeks DNA Sequencing Technologies Fit for Routine Laboratory and Medical Use
August 20, 2008 News Release - Advanced Sequencing Technology Awards 2007
- New Grants Bolster Efforts to Generate Faster and Cheaper Tools for DNA Sequencing
August 1, 2007 News Release - NHGRI Aims to Make DNA Sequencing Faster, More Cost Effective
October 2006 News Release - Advanced Sequencing Technology Awards 2005
- NHGRI Expands Effort to Revolutionize Sequencing Technologies
August 2005 Release - Advanced Sequencing Technology Awards 2004
- NHGRI Seeks Next Generation of Sequencing Technologies
October 2004 Release
Genome Technology Program Bibliography: Publications and Patents
NHGRI launched an ambitious program in 2004 to reduce the cost of full mammalian genome sequencing initially by 100-fold and subsequently by an additional 100-fold, aiming ultimately at about $1,000. Below, listed by Principal Investigator, are citations and links to many of the articles and patents resulting from this program and closely related research.
Genome Technology Program Publications and Patents
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Genome Technology Program Staff
Program Directors
Jeffery Schloss, Ph.D.
E-mail: schlossj@exchange.nih.gov
Bradley A. Ozenberger, Ph.D.
E-mail: bozenberger@mail.nih.gov
Mark Guyer, Ph.D.
E-mail: guyerm@exchange.nih.gov
Program Analyst
Christine Cutillo, Ph.D.
E-mail: cutilloc@mail.nih.gov
Address
National Human Genome Research Institute
National Institutes of Health
5635 Fishers Lane
Suite 4076, MSC 9305
Bethesda, MD 20892-9305
Phone: (301) 496-7531
Fax: (301) 480-2770
Last Updated: March 8, 2010
