Last updated: September 22, 2016
Future Opportunities for Genome Sequencing and Beyond: A Planning Workshop for the National Human Genome Research Institute
Future Opportunities for Genome Sequencing and Beyond:
A Planning Workshop for the National Human Genome Research Institute
July 28-29, 2014
Bethesda North Marriott & Conference Center
5701 Marinelli Road
North Bethesda, Md. 20852
(301) 822-9200
The National Human Genome Research Institute (NHGRI) sponsored the workshop - Future Opportunities for Genome Sequencing and Beyond: A Planning Workshop for the National Human Genome Research Institute - at the Bethesda North Marriott Hotel & Conference Center.
The objectives of the workshop were to:
- Discuss the scientific questions and opportunities that can be substantially addressed by large-scale genomics studies, starting with genome sequencing but also considering other genomic technologies.
- Consider options for future NHGRI programs that would address these questions and opportunities.
Workshop Report: Future Opportunities for Genome Sequencing and Beyond
Tweets from the Workshop: #GSPFuture
Monday, July 28, 2014
| Topic | Presenter/Moderator | |
|---|---|---|
| 1 | Welcome and Charge for the Workshop
| Eric Green, M.D., Ph.D NHGRI |
| 2 | Background and Orientation
| Adam Felsenfeld, Ph.D. NHGRI |
| 3 | Discovering Variants Conferring Risk for Common Diseases
| Michael Boehnke, Ph.D. University of Michigan |
| 4 | Discovering the Genomic Bases of Mendelian Diseases
| Roderick McInnes, M.D., Ph.D. Lady Davis Institute for Medical Research |
| 5 | Genomic Sequencing for Clinical Care
| Dan Roden, M.D. Vanderbilt University |
| 6 | Functional Genomics at Scale
| Joseph Ecker, Ph.D. Howard Hughes Medical Institute Salk Institute for Biological Studies |
| 7 | Discussion and Refinement of Opportunities
| Ewan Birney, Ph.D. European Bioinformatics Institute |
| 8 | Peptide Display and T-Cell Recognition Project
| David Haussler, Ph.D. University of California, Santa Cruz |
| 9 | Using the Negative Correlation Between Polygenic and Rare Variant Burdens for Common Disease To Improve Study Efficiency and Power Video Not Available | Slides | Nancy Cox, Ph.D. University of Chicago |
| 10 | The Human Cell Atlas
| Aviv Regev, Ph.D. Broad Institute |
| 11 | Measuring the Functional Consequences of Very Large Numbers of Human Genetic Variants
| Jay Shendure, M.D., Ph.D. University of Washington |
| 12 | Not Your Father's PDF: New Forms of Knowledge Representation for Genomic Sequence
| Daniel Masys, M.D., Ph.D. University of Washington |
Tuesday, July 29, 2014
| Topic | Presenter/Moderator | |
|---|---|---|
| 13 | Group 1: Understanding the Genetic Architecture of Health and Disease at Scale
| Eric Boerwinkle, Ph.D. University of Texas Health Sciences Center Michael Bamshad, Ph.D. University of Washington Adam Felsenfeld, Ph.D. NHGRI |
| 14 | Group 2: Integrating Genomic Variant Discovery with Function
| Richard Myers, Ph.D. HudsonAlpha Institute for Biotechnology Mike Pazin, Ph.D. NHGRI |
| 15 | Group 3: Clinical Genome Sequencing at Scale
| Heidi Rehm, Ph.D. Partners Healthcare Sharon Plon, M.D., Ph.D. Baylor College of Medicine |
| 16 | Group 4: Clinical Comparative Genomics at Scale
| Evan Eichler, Ph.D. University of Washington Andrew Clark, Ph.D. Cornell University |
| 17 | Introduction: "Scenarios"
| William M. Gelbart, Ph.D. Harvard University |
| 18 | Element 1: Understanding the Genetic Architecture of Health and Disease at Scale
| Adam Felsenfeld, Ph.D. NHGRI |
| 19 | Element 2: Integrating Genomic Variant Discovery and Function
| Carlos Bustamante, Ph.D. Stanford University |
| 20 | Element 3: Clinical Genome Sequencing at Scale
| James Evans, M.D., Ph.D. University of North Carolina at Chapel Hill |
| 21 | Discussion: Combining Strategic and Tactical Considerations
| Rex Chisholm, Ph.D. Northwestern University Adam Felsenfeld, Ph.D. NHGRI |
| 22 | Wrap-up
| Eric Green, M.D., Ph.D NHGRI |