Search Results
Event
Several NIH Institutes, Offices and Centers are partnering to host a two-day virtual workshop on May 28-29, 2024, to further explore the recommendations from the National Academies of Sciences, Engineering and Medicine (NASEM) 2023 report, Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field, with regards to legacy genomic data. 
Genetic Disorders
Thalassemia is a group of inherited diseases of the blood that affect a person's ability to produce hemoglobin, resulting in anemia.
… of Italian, Greek, Middle Eastern, Southern Asian and African Ancestry. The two main types of thalassemia are called … individuals of Southeast Asian, Chinese and Filipino ancestry, results in fetal or newborn death. A child who …
Research Training
The FLAGSHIP program aims to train early career postdoctoral scientists to become future leaders in genomic sciences research.
… been underrepresented in biomedical research (Blacks or African Americans, Hispanics or Latinos, American Indians or …
15 Ways Genomics Influences Our World
Genomics is fostering an appreciation for what our DNA means for our health, identities and culture.
… they might be abused. … The broad availability of genomic ancestry testing is influencing the way we think about the … (or how they described themselves). Large studies of African Americans in the United States have shown that their … Latino genomes in the United States show a mix of DNA from African, Native American, and European sources. It turns out …
Health
A polygenic risk score is one way by which people can learn what their risk of developing a disease is, based on the total number of genomics variants related to the disease.
… studies to date have examined individuals of European ancestry. Because of this issue, there may not be adequate … beyond polygenic risk scores. The percentage  of ancestry populations included in large-scale genomic studies … risk scores may only be valid and useful for European ancestry populations. More research is needed to derive the …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in May 2020.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites (U01) RFA-HG-20-002 - Polygenic Risk … (PRS) Methods and Analysis for Populations of Diverse Ancestry – Coordinating Center (U01) 19 Stakeholder … H3Africa Program Website Sequencing of the First African SARS-CoV-2 Genome 23 Ken Burns Presents The Gene: An …
File
… Genetics of Obesity, Diabetes, and Heart Disease in African Dias pora Populations Joan Marini, M.D., Ph.D. … for T ype 2 Diabetes; Whole Genome Methylation Analysis in African Americans Peter Williamson, M.D., Ph.D. National … of Hypertension and Obesity in Populations of African Ancestry Profess or Barry Freedman, M.D. Wake Forest School …
Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… population genomics research can be used to study human ancestry, migrations and health. … Population genomics is the …
Research Funding
The PAGE Consortium investigates ancestrally diverse populations to gain a better understanding of how genetic factors influence susceptibility to disease.
… causal genetic variants across approximately 100,000 African Americans, Asian Americans, American Indians, … efforts entirely on approximately 50,000 non-European ancestry individuals to better characterize how genetic …