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Chemistry and Biology: Partners in
Decoding the Genome

March 15-16, 2004
8:30 a.m. - 5:00 p.m.

Lecture Webcasts

Viewers outside the NIH network can download the latest free version of RealPlayer software from Real Networks.

March 15, 2003: 8:30 a.m. - 5:00 p.m.

Welcome
Elias Zerhouni, Director, National Institutes of Health

Greetings from Sponsoring Institutes
Jeremy Berg, Director, National Institute of General Medical Sciences

Morning Lectures:

Moderator: John Schwab
National Institute of General Medical Sciences

  • Christopher Austin, National Human Genome Research Institute
    Small Molecules and the NIH Roadmap

  • Daniel Kahne, Princeton University
    Glycopeptide Antibiotics and Cell Envelope Biogenesis

  • Stuart Schreiber, Harvard University
    Dissecting Disease Biology and Advancing Medicine with Small Molecules

  • Craig Crews, Yale University
    A Small Molecule Approach to Target Identification and Validation

  • Carolyn Bertozzi, University of California, Berkeley
    Chemical Approaches to Studying Protein Glycosylation

Afternoon Lectures:

Moderator: Christopher Austin
National Human Genome Research Institute

  • David Liu, Harvard University
    An Evolution-Based Approach to the Creation and Discovery of Functional Synthetic Molecules

  • Roger Tsien, University of California, San Diego
    Genetically and Proteolytically Targeted Sequences for Imaging from Ultrastructure to Whole Mammals

  • Jeremy Berg, National Institute of General Medical Sciences
    Chemical Approaches to Zinc Finger Protein Analysis and Design

  • Jon Ellman, University of California, Berkeley
    Combinatorial Chemistry Targeting Protein Families

Moderator: John Schwab
National Institute of General Medical Sciences

  • Gary Glick, University of Michigan
    Chemistry and Biology of Immunosuppressive Benzodiazepines

  • Stephen Fesik, Abbott Laboratories
    NMR-Based Screening of Fragment Libraries for Drug Discovery
March 16, 2003: 8:30 a.m. - 5:00 p.m.

Morning Lectures:

Moderator: John Schwab
National Institute of General Medical Sciences

  • Kevan Shokat, University of California, San Francisco
    Chemical Tools for Deciphering Cell Signaling Pathways

Moderator: John Beutler
National Cancer Institute

  • David Diller, Pharmacopeia
    The Role of Computation When Building Collections of Millions of Compounds

  • Virginia Cornish, Columbia University
    Co-opting Nature for Chemical Diversity

  • Dimitris Agrafiotis, 3-Dimensional Pharmaceuticals
    Molecular Informatics for the New Drug Discovery Enterprise

Afternoon Lectures:

Moderator: Carole Bewley
National Institute of Diabetes and Digestive and Kidney Diseases

  • Chaitan Khosla, Stanford University
    Discovery and Development of New Natural Product Drugs: The Example of Polyketides

  • Baldimero Olivera, University of Utah
    Conus Peptides: From Genes to Venoms to Drugs

  • Michael Organ, York University
    New Advances in the Screening of Compound Mixtures

Moderator: Christopher Austin
National Human Genome Research Institute

  • Alan Verkman, University of California, San Francisco
    Drug Discovery in Academia: CFTR Chloride Channel Inhibitors and Activators for Cystic Fibrosis

  • Eric Lander, The Broad Institute of MIT and Harvard

Closing Remarks
Alan Guttmacher, Deputy Director, National Human Genome Research Institute

Last updated: May 23, 2012