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The Cancer Genome Atlas 3rd Annual Scientific Symposium:

DNA double-helix and two researchers On May 12-13, 2014, The Cancer Genome Atlas (TCGA) held its third annual scientific symposium at Natcher Conference Center in Bethesda, Md. Through collaborative workshops, poster sessions and plenary presentations, TCGA investigators from around the world shared their novel biological discoveries, analytical methods and translational approaches using TCGA data.  
 

 
 

View symposium videos and slides from: May 12  | May 13

Monday, May 12, 2014

1 Opening
YouTube video Video
Matthew Meyerson, M.D., Ph.D.
Dana-Farber Cancer Institute

Marco Marra, Ph.D.
British Columbia Cancer Agency
2 Keynote Address
YouTube video Video
Robert Grossman, Ph.D.
University of Chicago
3 Session I Introduction
YouTube video Video
Han Liang, Ph.D.
University of Texas MD Anderson Cancer Center
4 Comprehensive and Integrative Genomic Characterization of Diffuse Lower Grade Gliomas
YouTube video Video | Slides PDF file
Daniel Brat, Ph.D.
Emory University School of Medicine
5 Using TCGA Data to Inform on Precision Medicine in Late Stage Cancer Settings
YouTube video Video | Slides PDF file
Andrew J. Mungall, Ph.D.
British Columbia Cancer Agency
6 The ICGC-TCGA DREAM Somatic Mutation Calling Challenge: Initial Results
YouTube video Video | Slides PDF file
Paul Boutros, Ph.D.
Ontario Institute for Cancer Research
7 Lessons Learned from the Genomic Characterization of Patient-Matched Frozen and Formalin Fixed, Paraffin-Embedded Tissues: Progress Update
YouTube video Video | Slides PDF file
Erik Zmuda, Ph.D.
Nationwide Children's Hospital
8 Domain-specific PIK3CA mutations affect different pathway activities across >3000 TCGA Pan-Cancer-12 tumors
YouTube video Video | Slides PDF file
Christopher Benz, M.D.
Buck Institute for Research on Aging
9 Comprehensive Molecular Profiling of Adrenocortical Carcinoma
YouTube video Video | Slides PDF file
Siyuan Zheng, Ph.D.
University of Texas M.D. Anderson Cancer Center
10 Session II Introduction
YouTube video Video
Josh Stuart, Ph.D.
University of California, Santa Cruz
11 Comprehensive Molecular Characterization of Chromophobe Renal Cell Carcinoma
YouTube video Video | Slides PDF file
Chad Creighton, Ph.D. 
Baylor College of Medicine
12 Prediction of Individualized Therapeutic Vulnerabilities In Cancer from Genomic Profiles
YouTube video Video | Slides PDF file
Bulent Arman Aksoy
Memorial Sloan-Kettering Cancer Center
13 Recurrent Epistates Define Tumor Methylome Differences
YouTube video Video | Slides PDF file
Huy Q. Dinh, Ph.D. 
University of Southern California
14 What do we learn from Pan-Cancer Subtyping?
YouTube video Video | Slides PDF file
Josh Stuart, Ph.D.
University of California, Santa Cruz
15 Profiling Long Intergenic Non-Coding RNA Interactions In The Cancer Genome
YouTube video Video | Slides PDF file
Samir B. Amin,  M.D. 
University of Texas MD Anderson Cancer Center
16 Multi-Omics Classification of Head and Neck Cancer Ties TP53 Mutation To 3p Loss
YouTube video Video | Slides PDF file
Andrew M. Gross 
University of California, San Diego

 

Tuesday, May 13, 2014

17 Session III Introduction
YouTube video Video
Peter Laird, Ph.D.
University of Southern California
18 Integrated Genomic Characterization of Papillary Thyroid Carcinoma 
YouTube video Video | Slides PDF file
Thomas J. Giordano M.D., Ph.D.
University of Michigan
19 Somatic Alterations In Clinically Relevant Cancer Genes Among 12 TCGA Tumor Types
YouTube video Video | Slides PDF file
Ali Amin-Mansour
Broad Institute
20 Inferring Intra-Tumor Heterogeneity from Whole-Genome/Exome Sequencing Data 
YouTube video Video | Slides PDF file
Layla Oesper, M.S. 
Brown University
21 Genomic Characterization of Invasive Lobular Breast Carcinoma
YouTube video Video | Slides PDF file
Michael L. Gatza, Ph.D.
The University of North Carolina at Chapel Hill
22 LineUp: Identifying Deleterious Mutations Using Protein Domain Alignment 
YouTube video Video | Slides PDF file
Brady Bernard, Ph.D. 
Institute for Systems Biology
23 Integrative Analysis of TCGA Data Reveals Wilms' Tumor 1 Mutation is a Driver of DNA Methylation in Acute Myeloid Leukemia 
YouTube video Video | Slides PDF file
Subarna Sinha, Ph.D. 
Stanford University
24 The Pan-Cancer Proteomic Landscape of The Cancer Genome Atlas Projects
YouTube video Video | Slides PDF file
Rehan Akbani, Ph.D. 
The University of Texas MD Anderson Cancer Center
25 Comprehensive Genomic Characterization of Cutaneous Melanoma
YouTube video Video | Slides PDF file
Ian R. Watson, Ph.D.
The University of Texas MD Anderson Cancer Center
26 Data Mining TCGA Breast and Ovarian Exomes for Novel Susceptibility Markers
YouTube video Video | Slides PDF file
John Martignetti, M.D., Ph.D.
Icahn School of Medicine at Mount Sinai
27 Discovery and Functional Characterization of Recurrent Gene Fusions from 4,932 Primary Tumor Transcriptomes Across 19 Human Cancers
YouTube video Video | Slides PDF file
Chai Bandlamudi, M.S. 
The University of Chicago
28 Widespread Genetic Epistasis Among Cancer Genes 
YouTube video Video | Slides PDF file
Audrey Q. Fu, Ph.D. 
The University of Chicago
29 Understanding the Evolution of Melanoma Epigenome 
YouTube video Video | Slides PDF file
Kadir C. Akdemir, Ph.D. 
The University of Texas MD Anderson Cancer Center
30 Comprehensive Molecular Characterization of Gastric Adenocarcinoma 
YouTube video Video | Slides PDF file
Adam Bass, M.D.
Dana-Farber Cancer Institute
31 Integrated Analysis of Metastatic Disease in Clear Cell Renal Cell Carcinoma: A Collaborative TCGA Analysis 
YouTube video Video | Slides PDF file
A. Ari Hakimi, M.D.
Memorial Sloan-Kettering Cancer Center
32 Multi-Center Mutation Calling in TCGA
YouTube video Video | Slides PDF file
David A. Wheeler, Ph.D. 
Baylor College of Medicine
33 Extensive Trans And cis-QTLs Revealed By Large-Scale Cancer Genome Analysis 
YouTube video Video | Slides PDF file
Kjong-Van Lehmann, Ph.D.
Memorial Sloan-Kettering Cancer Center
34 Pan-Cancer Analysis of APOBEC Mutagenesis 
YouTube video Video | Slides PDF file
Dmitry A. Gordenin, Ph.D. 
National Institute of Environmental Health Sciences, NIH
35 Integration of Multiple Data Types for Genomic Characterization of Virus-Associated Tumors
YouTube video Video | Slides PDF file
Matthew A. Wyczalkowski, Ph.D.
Washington University School of Medicine
36 Closing Remarks
YouTube video Video
Matthew Meyerson, M.D., Ph.D.
Dana-Farber Cancer Institute

Last updated: June 05, 2014