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Advancing Genomic Medicine Research (AGMR)

The AGMR program stimulates innovation and advance understanding of when, where and how best to implement the use of genomic information and technologies in clinical care.

Overview

Historically, NHGRI has largely funded genomic medicine research through multi-disciplinary consortia. The AGMR program expands NHGRI’s genomic medicine portfolio to include focused research projects that propose nimble, flexible approaches to problems in application or implementation of genomic medicine. AGMR investigators participate in at least one annual meeting, allowing for independent but synergistic efforts among grantees and promoting rapid sharing of successful approaches and resulting data.

Investigators

Names

Institution

Project Title

Aimé Lumaka ZolaUniversite De KinshasaAfrican Rare Diseases Initiative (ARDI): Advancing Genomic Medicine through rare diseases research in Africa
Sean DavidUniversity of ChicagoIntegrative Analyses of Clinical Pharmacogenetic Data to Prevent Hospital Readmission in Real-World Health Systems across Metropolitan Chicagoland
Sarah KnerrUniversity of WashingtonApplying Population Management Best Practices to Preventive Genomic Medicine
Iftikhar KulloMayo Clinic RochesterGenomic Medicine for Individuals from East Africa (GEMINEA)
Pankaj B. Agrawal
Margaret Graham Kemper Parker
Timothy Wei-Wen Yu
Boston Children's HospitalVIGOR: Virtual Genome Center for Infant Health
Lisa Bastarache
Douglas Ruderfer
Vanderbilt University Medical CenterTranslating the Clinical Knowledge of Mendelian Diseases to Real-World EHR Data to Improve Identification of Undiagnosed Patients
Hugo J. Bellen
Michael Francis Wangler
Baylor College of MedicineGenomic Medicine and Gene Function Implementation for an Underserved Population
Jonathan S. Berg
Laura Vogel Milko
University of North Carolina at Chapel HillAge-Based Genomic Screening in Newborns, Infants and Children: A Novel Paradigm in Public Health Genomics
Julio David DuarteUniversity of FloridaPreemptive Pharmacogenetic Testing in Medically Underserved Populations
Cong LiuColumbia University Health SciencesRESCUE: Rare Disease Detection and Escalation Support Via a Learning Health System
Gabor T. Marth
Martin Tristani-Firouzi
University of UtahCalypso: A Web Software System Supporting Team-Based, Longitudinal Genomic Diagnostic Care
Katherine L. Nathanson
Marylyn D. Ritchie
Robert A. Schnoll
University of PennsylvaniaUsing Behavioral Economics and Implementation Science to Advance the Use of Genomic Medicine Utilizing an EHR Infrastructure Across a Diverse Health System
Lori Ann OrlandoDuke UniversityDeploying a Genomic Medicine Risk Assessment Model for Diverse Primary Care Populations and Settings
Joseph F. Peterson
Jing Hao
David L. Veenstra
Vanderbilt University Medical CenterRational Integration of Polygenic Risk Scores (RIPS)
Kathryn A. PhillipsUniversity of California, San FranciscoBuilding the Evidence Base for Appropriate and Efficient Implementation of Emerging Genomic Tests for Disease Management and Screening
Marc S. WilliamsGeisinger ClinicReal-Time Genetic Diagnosis at the Point of Care
**Eric A. Boerwinkle, Samden Lhatoo, GQ ZhangUniversity of Texas Hlth Sci Ctr HoustonImplementation Science for Genomic Health Translation (INSIGHT)
**Renata Constance GallagherUniversity of California, San FranciscoToward DNA Sequencing as a Primary Newborn Screen for Treatable Disorders Not Amenable to Current Screening
**Catherine Astrid BrownsteinBoston Children's HospitalNavigating Online Patient Experiences of Genomic Medicine: Identifying and Overcoming Obstacles for African American Communities

**Past Grantees

 

More information about AGMR’s funded projects is available in NIH’s RePORTER.

Funding Opportunities

  • RFA-HG-23-032Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
    Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025
    Expiration Date: February 12, 2025
     
  • RFA-HG-23-033Advancing Genomic Medicine Research (R21 Clinical Trial Optional)
    Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025
    Expiration Date: February 12, 2025
     
  • RFA-HG-23-048: Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)
    Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025
    Expiration Date: February 12, 2025
     
  • NOT-HG-24-002: Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses
     
  • RFA-HG-20-036Advancing Genomic Medicine Research (Clinical Trial Optional) (R01)
    Due Dates: August 3, 2020; March 8, 2021; November 2, 2021; August 1, 2022; March 13, 2023
    Expiration Date: March 14, 2023

    NOT-HG-23-034Notice of Intent to Publish a Notice of Funding Opportunity for Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
     
  • RFA-HG-20-037Advancing Genomic Medicine Research (Clinical Trial Optional) (R21)
    Due Dates: August 3, 2020; March 8, 2021; November 2, 2021; August 1, 2022; March 13, 2023
    Expiration Date: March 14, 2023

    NOT-HG-23-035Notice of Intent to Publish a Notice of Funding Opportunity for Advancing Genomic Medicine Research (R21 Clinical Trial Optional)

Program Staff

Program Directors

Chang
Christine Q. Chang, M.P.H.
  • Program Director
  • Division of Genomic Medicine
Renee Rider
Renee Rider, M.S., J.D., LCGC
  • Program Director
  • Division of Genomic Medicine

Program Analysts

Jahnavi Narula
Jahnavi Narula, B.S.
  • Scientific Program Analyst
  • Division of Genome Sciences
Weini Ogbagiorgis
Weini Ogbagiorgis, B.S.
  • Scientific Program Analyst
  • Division of Genomic Medicine

Last updated: June 20, 2024