NHGRI recognizes leaders in diversity, equity, inclusion, and accessibility with new award
Last month, genomicists and genomics aficionados gathered in Hollywood, Florida, to immerse themselves in all-things genomics at the annual Advances in Genome Biology and Technology (AGBT) General Meeting. The warm, but windy weather welcomed scientists from around the world, who presented their genomics research covering a range of topics — from technology development to conservation biology. Long-read DNA sequencing and telomere-to-telomere genome sequencing efforts grabbed some of the spotlight, but short-read DNA sequencing technologies were, of course, ever-present. The AGBT General Meeting is always a wonderful event and a celebration that highlights the latest advances in genomics.
All the best,
In This Issue
- NHGRI recognizes leaders in diversity, equity, inclusion, and accessibility with new award
- Investigator-initiated research advances NHGRI’s scientific mission
- NIH seeks input for re-envisioning the postdoctoral research experience
- National Academies report strives to advance antiracism, diversity, equity, and inclusion science
- Student tweets concisely communicate complex genomic topics
- Genetic Engineering & Biotechnology News virtual conference showcases the state of genomics
Genomics Research Spotlight
A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes
Toh et al.
BMC Biol 20, 245 (2022). PMC9641963
The Nile rat is a promising resource for diabetes research. Other rodent species require genomic modifications to model diabetes and cannot properly model pre-diabetes or early diabetes, but the Nile rat naturally develops diabetes when put on a high-energy diet. However, the Nile rat’s usefulness in research has been hindered by the lack of a reference genome sequence for the species. Now, NHGRI researchers and collaborators have assembled a high-quality Nile rat genome sequence. This new sequence reveals over 3,000 genes in the Nile rat genome that are related to human genes involved in type 2 diabetes. The Nile rat genome sequence will allow researchers to connect the development and symptoms of diabetes and treatment responses to specific genes, facilitating powerful molecular biology studies exploring the onset and care of diabetes.
This research was supported by the NHGRI Intramural Research Program in the laboratory of Adam Phillippy, Ph.D., senior investigator in the Computational and Statistical Genomics Branch and head of the Genome Informatics Section.
About The Genomics Landscape
A monthly update from the NHGRI Director on activities and accomplishments from the institute and the field of genomics.
Last updated: March 2, 2023