Genomic Medicine XIV: Genomic Learning Healthcare Systems
Event Details
On August 31 - September 1, 2022, the National Human Genome Research Institute (NHGRI) sponsored its 14th Genomic Medicine meeting, Genomic Medicine XIV: Genomic Learning Healthcare Systems.
This meeting discussed progress and identify generalizable solutions to the challenges of implementing genomic medicine we have encountered since the 2015 National Academy of Medicine's Genomics-Enabled Learning Health Care Systems workshop. Persistent barriers and evidence gaps were examined as opportunities for additional research.
The objectives of the meeting were to:
- Explore real-world examples of how genomic learning healthcare systems (gLHS) apply cycles of genomic medicine implementation, evaluation, adjustment and updated implementation practices across delivery systems.
- Examine barriers and identify potential solutions, with a focus on lessons learned from effective gLHS and their potential transportability to other settings.
- Determine ways to develop and share solutions and form collaborations to facilitate research on implementing gLHS.
Meeting Booklet (PDF)
Executive Summary (PDF)
Meeting Summary (PDF)
Genomic Medicine Working Group Discussion on Genomic Medicine XIV (PDF)
to
Virtual
Recorded Video
Wednesday, August 31, 2022
| Time | Topic | Speaker(s) |
|---|---|---|
| 11:00 a.m. | Welcome and Introductions | |
| Overview of National Academy of Medicine's 2015 Workshop, Genomics-Enabled Learning Health Care Systems | Pat Deverka | |
| Structure, Goals and Products of NHGRI Genomic Medicine Meetings | Teri Manolio | |
| 11:15 a.m. | Session 1: Laying the Groundwork | Moderators: Rex Chisholm Renee Rider |
| Keynote: The State of Genomic Learning Healthcare Systems (25 min) | Peter Hulick | |
| Overview of gLHS Barriers (10 min) | Teri Manolio | |
| Panel Discussion (55 min) | Adam Buchanan Gai Elhanan Casey Overby-Taylor Bruce Korf | |
| 12:45 p.m. | Break | |
| 12:55 p.m. | Session 2: IT Infrastructure | Moderators: Carol Bult Christopher Chute |
| Clinical Informatics Recommendations From GM XIII (15 min) | Ken Wiley | |
| Integrating Genomic Results Into EHRs (15 min) | Travis Osterman | |
| Population-Based Clinical Decision Support for Precision Medicine (15 min) | Guilherme Del Fiol | |
| Discussion (45 min) | ||
| 2:25 p.m. | Break | |
| 2:55 p.m. | Session 3: The Role of gLHS in Increasing Health Equity and Access to Genomic Healthcare | Moderators: Gail Jarvik Karriem Watson |
| Identifying Biases in gLHS Data and Implementation (15 min) | Janina Jeff Latrice Landry | |
| Diverse Patient and Provider Engagement in gLHS (15 min) | Carol Horowitz | |
| Facilitating gLHS through Patient Access to Genomic Information (15 min) | Deven McGraw | |
| Discussion (60 min) | ||
| 4:55 p.m. | Adjourn Day 1 | |
Thursday, September 1, 2022
| Time | Topic | Speaker(s) |
|---|---|---|
| 11:00 a.m. | Welcome | |
| Day 1 Recap | Pat Deverka Teri Manolio | |
| 11:10 a.m. | Session 4: Enabling Providers to Implement Genomic Knowledge | Moderators: Susanne Haga Robb Rowley |
| Genomic Medicine Track for Internal Medicine Trainees (15 min) | Noura Abul-Husn | |
| Improving Access to Genomics in Clinical Practice (15 min) | Rizwan Hamid | |
| Scalable Solutions for Genetic Counseling (15 min) | Cynthia A. James | |
| Genomic Medicine Implementation in the VA Healthcare System (15 min) | Jason Vassy | |
| Discussion (45 min) | ||
| 1:10 p.m. | Break | |
| 1:30 p.m. | Session 5: Establishing and Sustaining gLHS | Moderators: Erin Ramos Krystal Tsosie |
| Generating Evidence of Effectiveness and Value (15 min) | Howard McLeod | |
| Genomic Learning Healthcare Systems and Payers (15 min) | Nancy Mendelsohn | |
| Progress in the Integration of Personalized Medicine and Developing Common Metrics (15 min) | Daryl Pritchard | |
| Discussion (45 min) | ||
| 3:00 p.m. | Break | |
| 3:10 p.m. | Session 6: Realizing the Promise of gLHS | Moderators: Pat Deverka Teri Manolio |
| Turning gLHS Data into Knowledge (15 min) | Heidi Rehm | |
| Creation of a Virtuous Cycle to Realize the gLHS (15 min) | Marc S. Williams | |
| Scaling the Genomics Enabled Learning Health System to Optimize Research and Clinical Care (15 min) | Geoff Ginsburg | |
| Discussion (30 min) | ||
| 4:25 p.m. | Summary and Next Steps | Pat Deverka Teri Manolio |
| 5:00 p.m. | Adjourn Day 2 | |
Follow-Up Working Group
Last updated: March 6, 2023