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Scientists are exploring the genomic and clinical profiles of people with RUNX1 familial platelet disorder.
… cancers, such as myelodysplastic syndrome, acute myeloid leukemia and acute lymphoblastic leukemia. Many people with this disorder may also have skin … there features that might predict if someone would develop leukemia?” … In the first study, published in the journal …
Profile
After major advances in hematology, David Bodine retires with an eye towards mentorship and a garden
David Bodine, founder of the Hematopoiesis Section and chief of the Genetics and Molecular Biology Branch, advanced the fields of gene therapy and hematology in his 38 years at the NIH. Now, he plans to continue his contributions to science as an emeritus and through training the next generation of scientists.
… and ask, “Why does that one stem cell go nuts and become leukemia? Is it because of where it is, or is it because of … If you could then change the microenvironment and cure leukemia that way, it'd be a lot better than chemotherapy. … …
For Patients and Families
Genetic research is creating new ways for people to take action and prevent disease and new ways to treat disease through personalized medicine.
… in tumors. Children with a common type of childhood leukemia can be tested to find the right doses of …
For Patients and Families
Pharmacogenomics combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.
… (Purinethol) to patients with acute lymphoblastic leukemia. Some people have a genetic variant that interferes …
Genetic Disorders
Severe Combined Immunodeficiency is a severe, genetic condition of the immune system.
… a French gene-therapy experiment had developed a type of leukemia. It was soon discovered that the mechanism used to …