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15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… diagnosed with a blood cancer called acute lymphoblastic leukemia (or ALL) in 2003, when he was in his fourth year of … This led him to specialize in treating patients with leukemia, and studying the disease in the laboratory. While … better results by Monday. After a number of weeks, the leukemia cells were no longer detectable in his blood, …
Profile
After major advances in hematology, David Bodine retires with an eye towards mentorship and a garden
David Bodine, founder of the Hematopoiesis Section and chief of the Genetics and Molecular Biology Branch, advanced the fields of gene therapy and hematology in his 38 years at the NIH. Now, he plans to continue his contributions to science as an emeritus and through training the next generation of scientists.
… and ask, “Why does that one stem cell go nuts and become leukemia? Is it because of where it is, or is it because of … If you could then change the microenvironment and cure leukemia that way, it'd be a lot better than chemotherapy. … …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… has been linked to a range of diseases, including leukemia, lymphomas, and other types of cancer, but these …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… (Purinethol) to patients with acute lymphoblastic leukemia. Some people have a genetic variant that interferes … of the treatment options for childhood acute lymphoblastic leukemia [cancer.gov] is stem cell transplantation therapy. …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Layla received a gene editing treatment to help her fight leukemia, a type of cancer. These scientists did not use …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… designed to treat a blood cancer called chronic myeloid leukemia (CML). CML occurs because of a single genetic glitch …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… to serious problems. For example, in humans, one type of leukemia and some other cancers are caused by defective …
The Genomics Landscape
In the June 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D. details the upcoming appointment of acting NHGRI Deputy Director, Vence Bonham Jr., J.D. and what it means for the institute.
… projects, including positional cloning of a fusion gene in leukemia, the identification of the familial Mediterranean …