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- Developmental Genotype-Tissue Expression (dGTEx)1
- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
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Fact Sheets
Cloning describes a number of different processes that can be used to produce genetically identical copies of a biological entity.
… … There are three different types of artificial cloning: gene cloning, reproductive cloning and therapeutic cloning. Gene cloning produces copies of genes or segments of DNA. … creating tissues to replace injured or diseased tissues. Gene cloning, also known as DNA cloning, is a very different …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… about 85 percent of their genes! By changing a single gene or multiple genes in a mouse, scientists can observe how … genomic basis of deafness.  … Scientists are developing gene therapies  - treatments involving genome editing - to … and diabetes. There are two different categories of gene therapies: germline therapy and somatic therapy. …
Policy Issues
Patients with genetic disorders and members of the public have diverse about germline genome editing.
… a survey  to understand the public's feelings about gene editing for newborns that would give them a reduced risk … Though they found some enthusiasm among the public about gene editing, they also found that about two-thirds of U.S. … public is about evenly divided on whether they would use gene editing for their own child The public is about evenly …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… will aid the development of new treatments, including gene therapy . … Scientists have had the knowledge and … fraction of time and price. … [1] Capecchi, M. R. (2005). Gene targeting in mice: functional analysis of the mammalian … Gallardo, V., . . . Burgess, S. M. (2015). High-throughput gene targeting and phenotyping in zebrafish using …
Fact Sheets
Fluorescence in situ hybridization (FISH) provides researchers with a way to visualize and map the genetic material in an individual's cell.
… help a researcher or clinician identify where a particular gene falls within an individual's chromosomes. The first step … of single-stranded DNA that match a portion of the gene the researcher is looking for. These are called probes. … useful when scientists have isolated a small portion of a gene and want to determine on which chromosome the gene is …
Fact Sheets
Chromosome abnormalities can either be numerical or structural and usually occur when there is an error in cell division.
Infographic
The X chromosome is part of sexual development and many other biological processes, including how some cats get their distinctive coat colors.
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… ​ … Synthetic Biology, Synthetic DNA, Genetic Engineering, Gene Editing, Genome Editing … Synthetic biology is a field …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… that contains instructions to make a protein is known as a gene. The size of a gene may vary greatly, ranging from about 1,000 bases to 1 …