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- Developmental Genotype-Tissue Expression (dGTEx)1
- Multi-Omics for Health and Disease (Multi-Omics)1
- Ethical, Legal and Social Implications (ELSI) Research Program6
- Genomics-Enabled Learning Health Systems (gLHS)2
- Genetic Architecture of Complex Traits1
- Genome Technology Program5
- Enhancing Opportunities in Computational Genomics and Data Science1
- Human Genome Reference Program (HGRP)2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Advancing Genomic Medicine Research (AGMR)1
- Encyclopedia of DNA Elements (ENCODE) Project1
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- Clinical Genome (ClinGen) Resource1
- Genomic Innovator Awards2
- Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)2
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
News Release
New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome.
… the most comprehensive reference sequence of the human genome. The awards, made over five years pending the … availability of funds, are managed by the National Human Genome Research Institute (NHGRI), part of the National … The funds are necessary for making advances in DNA sequencing technology and computational methods possible. As …
About Genomics
February 15, 2021 marks the 20-year anniversary of publications reporting the draft human genome sequence.
… papers that revealed the first detailed look at the human genome's nearly complete sequence. A part of the Human Genome Project, these studies launched a new era in biomedicine that has since achieved ever-dropping sequencing costs, improved diagnosis of genetic disorders and …
Media Advisory
The National Institutes of Health (NIH) will host researchers from the Telomere-to-Telomere (T2T) consortium, who have now sequenced the remaining 8% of DNA that was unable to be sequenced by the Human Genome Project and has eluded researchers for nearly two decades.
… discuss the first complete, gapless sequence of a human genome via virtual conference call on March 31. … The … 8% of DNA that was unable to be sequenced by the Human Genome Project and has eluded researchers for nearly two … What: Virtual press conference to announce T2T consortium sequencing a complete human genome Moderator: Eric Green, …
About Genomics
An interactive timeline listing key moments from the history of the project.
… and values of NHGRI. … Completed in April 2003, the Human Genome Project gave us the ability to read nature's complete …  1984-86 Early meetings assess the feasibility of a Human Genome Project. More + 1984-86 In December 1984, the U.S. … hold " The Santa Cruz Workshop " on human genome sequencing. In March 1986, the DOE Office of Health and …
News Release
The Telomere-to-Telomere (T2T) Consortium has generated the first truly complete sequence of a human Y chromosome - the final human chromosome to be fully sequenced.
… a team of researchers funded by the National Human Genome Research Institute (NHGRI), part of the National … involved in human sexual development are spread across the genome and very complex, giving rise to the array of human … sequence particularly difficult to complete. Assembling sequencing data is like trying to read a long book cut into …
The Genomics Landscape
In the September 2023 edition of The Genomics Landscape, NHGRI Director Eric Green, recaps the April 2023 virtual reunion of the leaders of the five genome-sequencing centers (G5), where they tell the untold story on how they ushered the Human Genome Project across the finish line in 2003.
… 100th meeting of the National Advisory Council for Human Genome Research (NACHGR) will take place on September 18 and … demonstrate the importance of looking at the entire genome, not just the parts that code for protein, when … dubbed the ‘G5’ and included leaders of the five genome-sequencing centers that produced the largest amount of human …
The Genomics Landscape
In the September 3, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about the Impact of Genomic Variation on Function (IGVF) Consortium, the 2020 Genomic Innovator Awards and more.
… up to the 30th anniversary of the launch of the Human Genome Project in October 2020. Check out the latest oral … 91st meeting of the National Advisory Council for Human Genome Research will take place on September 14-15. As usual, … in biology is understanding how genomic variation affects genome function to influence phenotypes. NHGRI recently …
News Release
Small businesses with NHGRI grants were instrumental in contributing to the completion of the human genome sequence, redefining the future of genomics.
… in contributing to the completion of the human genome sequence, redefining the future of genomics. … When … grants provided by institutes such as the National Human Genome Research Institute (NHGRI), among others. Small … development ecosystem. Until recently, almost all genome sequencing methods required researchers to extract DNA from a …
News Release
On June 26, 2000, nearly 10 years into the 13-year project, President Bill Clinton announced an important milestone for the Human Genome Project at a major White House ceremony.
… Clinton june 26, 2000 … The signature goal of the Human Genome Project (HGP) was to generate a sequence of the three … the completion of a working draft sequence of the human genome.   Standing beside President Clinton was Francis … Richard Wilson, Ph.D., who was co-director of the Genome Sequencing Center at Washington University School of Medicine …
The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… Green, M.D., Ph.D. … Thirty years ago, today, the Human Genome Project (HGP) officially launched. I was there on the … been awarded one of the first center grants for the Human Genome Project by the then-named National Center for Human … These would be steppingstones to the signature goal of sequencing the entire human genome. Previous work had started …