Search Results
Facet (Page)
Refine Your Search
Audiences
Content Formats
Events
Sections
Divisions
Programs
- Multi-Omics for Health and Disease (Multi-Omics)1
- Ethical, Legal and Social Implications (ELSI) Research Program2
- Genomics-Enabled Learning Health Systems (gLHS)2
- Genome Technology Program1
- Impact of Genomic Variation on Function (IGVF) Consortium1
- Clinical Genome (ClinGen) Resource1
- Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
Event
On June 17-18, 2021, NHGRI hosts a workshop, Multi-Omics in Health and Disease: Current Applications, Challenges and Future Directions.
… the Stage - Application of multi-omics to study health and disease Moderator: Judy Cho, Icahn School of Medicine at Mt. … 1: Multi-omics Integration to Understand Health and Disease Nancy Cox, Vanderbilt University 2:15 - 2:45 p.m. … NHGRI 1:10 - 1:25 p.m. Presentation 1: Using Polygenic Risk Scores Combined With Multi-omics Data to Provide …
Policy Issues
Genome editing is currently being applied to research on cancer, mental health, rare diseases, and many other disease areas.
… on cancer, mental health, rare diseases, and many other disease areas. … Basic research exploring human and nonhuman … to help scientists understand the basic biology underlying disease, as well as to discover new possible therapeutic … begin evaluating the safety of potential treatments. The risk of off-target edits, or unintended edits, and their …
Event
NHGRI workshop seeking scientific perspectives for relating genomic variation to human phenotype.
… a.m. NHGRI's Current Approach to "Variant to Function to Disease" NHGRI Staff 11:25 - 12:10 p.m. Current State of the … if any, is needed to study Mendelian and common disease, and what should NHGRI do in this area? Why? … of Variation Associated with Human Health and Disease Panel: Barbara Stranger Anshul Kundaje David Valle …
Event
The 2018 meeting focused on KOMP's collaborations with various human disease gene discovery programs.
… on KOMP's collaborations with various human disease gene discovery programs. The day featured talks and … Research Program (Kids First) and the Undiagnosed Disease Network (UDN). … Rockville Hilton Hotel … MD … 1750 … focused on KOMP's collaborations with various human disease gene discovery programs. … The 2018 meeting focused …
Policy Issues
Participating in genomics research is an opportunity to support exploration of the genome and help scientists understand, prevent, detect and treat disease.
… mission to understand, prevent, detect and better treat disease. In some cases, research participants may also gain some individual benefit, such as diagnosis of a disease or access to a treatment in development. … A wide … purpose of any study and any potential personal benefit or risk from participation. Consider the following list of …
Policy Issues
Patients with genetic disorders and members of the public have diverse about germline genome editing.
… patients suffering from conditions such as Huntington disease  believe strongly that it should be used to prevent … gene editing for newborns that would give them a reduced risk of serious diseases during their lives. The survey noted … DNA Editing, Gene Therapy, Genetic Disorder, Genetic Disease, CRISPR-Cas9, CRISPR … Patients with genetic …
Policy Issues
The Genome Statute and Legislation Database is comprised of state statutes and bills introduced during U.S. state legislative sessions.
… Genetic Information Non-discrimination Act, GINA, Genetic Disease, Workplace Discrimination, Laws About Genetics, Gene …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… lead to changes in physical traits, like eye color, and disease risk. Scientists use different technologies to do this. … … leading to changes in physical traits, like eye color, and disease risk. Scientists use different technologies to do …
The Informed Consent Resource
Explore genomics-relevant considerations for informed consent and guidance on how to approach them.
… in which genomics is the primary aim, and for some disease-specific research that considers genomics, … they are being recruited because they have a disease risk, which could come as a surprise to them. Writing consent … about their participation in genomics research on assessments of the risks and benefits of a given study for …
Policies and Guidance
A webpage with information and associated FAQs that describe various expectations for data sharing that are specific to NHGRI-supported studies.
… of research participants, maintain privacy, and mitigate risk, especially for vulnerable or marginalized groups. NHGRI … would be compromised or would place them at greater risk of re-identification or suffering harm, and 2) … and for what purposes (e.g., general research use, disease-specific research use) and whether sharing will occur …