Search Results
Facet (Page)
Refine Your Search
Audiences
Content Formats
Events
Sections
Divisions
Programs
- Developmental Genotype-Tissue Expression (dGTEx)1
- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Clinical Genome (ClinGen) Resource1
- Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… genome-editing research. … In light of recent advances in gene-editing research and technologies, the National … decision making for the responsible use of human gene-editing research. This initiative examined the clinical, ethical, legal and social implications of human gene editing. Their efforts included an international summit …
Policy Issues
Genome editing is currently being applied to research on cancer, mental health, rare diseases, and many other disease areas.
… targets. Although excitement about the potential for gene therapy has grown tremendously since the discovery of … physicians might eventually be able to prescribe targeted gene therapy to make corrections to patient genomes and … reverse disease. … There are two different categories of gene therapies: germline  therapy and somatic  therapy. …
Policy Issues
Most ethical discussions about genome editing center on human germline editing because changes are passed down to future generations.
… attempted at this time, but that studies that would make gene therapy  safe and effective should continue. 1 , 2  Most … in December 2015 with the International Summit on Human Gene Editing  in Washington, DC. For more information on this … modify DNA in the genome. Other groups also use the term "gene editing." In general, these terms are used …
Policy Issues
In June 2013, the Supreme Court determined that DNA in its natural form cannot be patented.
… discoveries. Since then, the core of the debate over gene patents has been whether or not the discovery of a gene or sequence of DNA rises to the level of invention … art to which said subject matter pertains." In the case of gene patents, critics have pointed out that such patents fail …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… about 85 percent of their genes! By changing a single gene or multiple genes in a mouse, scientists can observe how … genomic basis of deafness.  … Scientists are developing gene therapies  - treatments involving genome editing - to … and diabetes. There are two different categories of gene therapies: germline therapy and somatic therapy. …
Policy Issues
Patients with genetic disorders and members of the public have diverse about germline genome editing.
… a survey  to understand the public's feelings about gene editing for newborns that would give them a reduced risk … Though they found some enthusiasm among the public about gene editing, they also found that about two-thirds of U.S. … public is about evenly divided on whether they would use gene editing for their own child The public is about evenly …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
​
… will aid the development of new treatments, including gene therapy . … Scientists have had the knowledge and … fraction of time and price. … [1] Capecchi, M. R. (2005). Gene targeting in mice: functional analysis of the mammalian … Gallardo, V., . . . Burgess, S. M. (2015). High-throughput gene targeting and phenotyping in zebrafish using …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… ​ … Synthetic Biology, Synthetic DNA, Genetic Engineering, Gene Editing, Genome Editing … Synthetic biology is a field …
Policy Issues
The Genome Statute and Legislation Database is comprised of state statutes and bills introduced during U.S. state legislative sessions.
… Disease, Workplace Discrimination, Laws About Genetics, Gene Patents … The Genome Statute and Legislation Database is …
Policies and Guidance
A webpage with information and associated FAQs that describe various expectations for data sharing that are specific to NHGRI-supported studies.
… measures Level 3: Analysis to identify genetic variants, gene expression patterns, or other features of the data set Level …