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News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… In recent research published online in July in the journal Leukemia, Paul Liu, M.D., Ph.D., asenior investigator and … with a specific kind of relapse-prone acute myeloid leukemia (AML). Though AML is generally thought to be a … American Cancer Society. "We're trying to understand why leukemia patients relapse, and if there are any DNA-level …
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… diagnosed with a blood cancer called acute lymphoblastic leukemia (or ALL) in 2003, when he was in his fourth year of … This led him to specialize in treating patients with leukemia, and studying the disease in the laboratory. While … better results by Monday. After a number of weeks, the leukemia cells were no longer detectable in his blood, …
News Release
Scientists are exploring the genomic and clinical profiles of people with RUNX1 familial platelet disorder.
… cancers, such as myelodysplastic syndrome, acute myeloid leukemia and acute lymphoblastic leukemia. Many people with this disorder may also have skin … there features that might predict if someone would develop leukemia?” … In the first study, published in the journal …
Profile
After major advances in hematology, David Bodine retires with an eye towards mentorship and a garden
David Bodine, founder of the Hematopoiesis Section and chief of the Genetics and Molecular Biology Branch, advanced the fields of gene therapy and hematology in his 38 years at the NIH. Now, he plans to continue his contributions to science as an emeritus and through training the next generation of scientists.
… and ask, “Why does that one stem cell go nuts and become leukemia? Is it because of where it is, or is it because of … If you could then change the microenvironment and cure leukemia that way, it'd be a lot better than chemotherapy. … …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… has been linked to a range of diseases, including leukemia, lymphomas, and other types of cancer, but these …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… (Purinethol) to patients with acute lymphoblastic leukemia. Some people have a genetic variant that interferes … of the treatment options for childhood acute lymphoblastic leukemia [cancer.gov] is stem cell transplantation therapy. …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… changes that lead to certain blood cancers, such as leukemia. Although Dr. Liu acknowledged that the zebrafish is not a proven model for leukemia, its transparent embryos develop in the water away …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… hope to develop new therapies to treat patients with leukemia using their own iPSCs. We encourage other …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… cancers, sarcomas, colon cancers, bladder cancers and leukemia. Future studies are looking towards detecting the …
For Patients and Families
Genetic research is creating new ways for people to take action and prevent disease and new ways to treat disease through personalized medicine.
… in tumors. Children with a common type of childhood leukemia can be tested to find the right doses of …