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News Release
Researchers with support from NIH will conduct research into the genetic underpinnings of Alzheimer's disease.
… that have been at the forefront of research in Alzheimer's genetics: University of Pennsylvania, Philadelphia; Case … primary federal agency conducting and supporting basic, clinical, and translational medical research, and is …
The Genomics Landscape
In the July 2023 edition of The Genomics Landscape, NHGRI Director Eric Green describes the evolution of the NHGRI Intramural Research program over the last three decades talks about its future in conducting truly exceptional basic, translational, and clinical genomics research.
… to have recently awarded the American Society of Human Genetics (ASHG) over $7 million to support the new Genomics … of conducting truly exceptional basic, translational, and clinical genomics research. The IRP houses over 60 … of trainees across the full spectrum of research and clinical domains. The training opportunities within the IRP …
News Release
NIH researchers identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood.
… and Digestive and Kidney Diseases, as well as the NIH Clinical Center. NHGRI is one of the 27 institutes and … primary federal agency conducting and supporting basic, clinical, and translational medical research, and is …
News Release
When it comes to Attention-Deficit/Hyperactivity Disorder (ADHD), genetics do make an impact.
… comes to Attention-Deficit/Hyperactivity Disorder (ADHD), genetics do make an impact. … ADHD is as heritable as … comes to Attention-Deficit/Hyperactivity Disorder (ADHD), genetics do make an impact. … When it comes to Attention-Deficit/Hyperactivity Disorder (ADHD), genetics do make an impact. … News Release …
Event
On November 1-5, 2023, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.  The annual meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics. 
… PB5035 Rebekah Waikel Generative methods for Pediatric Genetics Education. PB2385 Edmond Wonkam Tingang Genome-Wide … with Gaucher disease PB4630 Oleg Shchelochkov Genomic and Clinical Correlates of Plasma Urate in the “All of Us” … HPS-1 pulmonary fibrosis PB2027 Zo Bly The landscape of clinical sequencing in diverse populations: lessons learned …
News Release
NIH will award $38.5 million over five years to the Developmental Genotype-Tissue Expression (dGTEx) project, which aims to build a widely available resource of human developmental gene expression in a multitude of tissues for use in basic and clinical research.
… many types of tissues from children for use in basic and clinical research. “There’s still so much we don’t know about … expression in a multitude of tissues for use in basic and clinical research. … NIH will award $38.5 million over five … expression in a multitude of tissues for use in basic and clinical research. … News Release …
News Release
A simple blood draw is replacing a giant needle to the belly for testing their fetuses for a range of genetic disorders.
News Release
NHGRI researchers have generated the largest catalog of genetic variants associated with physical traits for domesticated dog breeds.
… of dog breeds points toward the major role played by genetics in shaping such variation in dogs. … The Power of … the results, we've learned some of the fascinating genetics behind the variability observed in the world's 450 … in dogs than in humans, and eventually helping with clinical intervention in human patients. Such canine clues …
News Release
Research studies are now using polygenic risk scores to determine a person’s inherited risk for certain diseases, but there are inconsistencies in how these scores are calculated. NHGRI has published guidelines in Nature for how these scores should be reported.
… to compromise the adoption of polygenic risk scores in clinical care. To address this concern, the research teams, … in their studies. This framework — created by NHGRI’s Clinical Genome Resource's (ClinGen) Complex Disease Working … scores and determine which ones are ready to be used in clinical care." A real challenge is that the research …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… as adrenergic receptors. The study, published in  Nature Genetics , is one of the largest such genomic studies of … which are more likely to be effective.” To understand the genetics of blood pressure, the researchers combined four … shows that these big genome-wide association studies have clinical relevance for finding new drug targets and are …