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News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… of Health has awarded eight grants as part of the Genotype-Tissue Expression (GTEx) project to explore how human genes are …
News Release
Researchers funded by NIH have completed a detailed atlas documenting stretches of human DNA that influence gene expression.
… documenting the stretches of human DNA that influence gene expression - a key way in which a person's genome gives rise … types. … The atlas is the culmination of work from the Genotype-Tissue Expression (GTEx) Consortium, established to catalog …
News Release
NIH will award $38.5 million over five years to the Developmental Genotype-Tissue Expression (dGTEx) project, which aims to build a widely available resource of human developmental gene expression in a multitude of tissues for use in basic and clinical research.
… … The project will increase our understanding of how gene expression is regulated over time. … Eleven years ago, … Health (NIH) saw a gap in the availability of high-quality tissue samples and information on gene expression — important … bodies. In response to this realization, they began the Genotype-Tissue Expression (GTEx) consortium, which …
News Release
NIH researchers have created a data resource show how differences in an individual's genome can affect gene activity and contribute to disease.
… … Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and …
Event
NHGRI and NICHD program staff will hold a pre-application interactive Q&A webinar for the Developmental Genotype-Tissue Expression Project funding opportunities and answer questions from prospective applicants.
… LDACC and BPC both be engaged together in designing the tissue/sample specific sampling SOP protocols? Yes, the … work with AnVIL ? The LDACC will deposit data from gene expression and genotyping analyses in the AnVIL on a timely … Analysis, and Coordinating Center for the Developmental Genotype-Tissue Expression Project: Jyoti Dayal, M.S. …
News Release
NIH researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), found that individuals diagnosed with ADHD had differences in genes that code for known chemicals that brain cells use to communicate.
… this is the first study to use postmortem human brain tissue to investigate ADHD. Other approaches to studying … specific genes are turned on or off, also known as gene expression . They studied two connected brain regions … studies are rare because of the limited donation of brain tissue but are incredibly valuable because they provide …
News Release
Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… Of DNA Elements (modENCODE) Consortium studied how gene expression patterns and regulatory proteins that help … genes and regulatory elements that control gene expression. The current work builds on initial catalogs … (or readouts) in a genome. They used large amounts of gene expression data generated in the ENCODE and modENCODE …
The Genomics Landscape
In the October 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., introduces us to new scientific director Charles Rotimi, Ph.D., his background and prior accomplishments.
… $38.5 million over five years to support the Developmental Genotype-Tissue Expression (dGTEx) project, with funding from NHGRI, the …
The Genomics Landscape
In the May 2019 edition of The Genomics Landscape, NHGRI Director Eric Green recaps activities from National DNA Day 2019.
… clinical outcomes when prescribed medication guided by genotype-specific (i.e., pharmacogenomics) data. More … and helped to lead the NIH Common Fund’s Genotype-Tissue Expression (GTEx) project . Over the years, Jeff was an …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
… research. Dr. Troyer also co-managed the Developmental Genotype-Tissue Expression (dGTEx) program, which is establishing a resource …