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Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… genome-editing research. … In light of recent advances in gene-editing research and technologies, the National … decision making for the responsible use of human gene-editing research. This initiative examined the clinical, … of gene editing, germline modifications, somatic cell therapy, societal implications, international perspectives, …
Policy Issues
Most ethical discussions about genome editing center on human germline editing because changes are passed down to future generations.
… attempted at this time, but that studies that would make gene therapy safe and effective should continue. 1 , 2 Most … in December 2015 with the International Summit on Human Gene Editing in Washington, DC. For more information on this …
Policy Issues
Genome editing is currently being applied to research on cancer, mental health, rare diseases, and many other disease areas.
… targets. Although excitement about the potential for gene therapy has grown tremendously since the discovery of CRISPR, … physicians might eventually be able to prescribe targeted gene therapy to make corrections to patient genomes and …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… about 85 percent of their genes! By changing a single gene or multiple genes in a mouse, scientists can observe how … genomic basis of deafness. … Scientists are developing gene therapies - treatments involving genome editing - to … are two different categories of gene therapies: germline therapy and somatic therapy. Germline therapies change DNA in …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
… will aid the development of new treatments, including gene therapy . … Scientists have had the knowledge and ability to … fraction of time and price. … [1] Capecchi, M. R. (2005). Gene targeting in mice: functional analysis of the mammalian …
Policy Issues
Patients with genetic disorders and members of the public have diverse about germline genome editing.
… a survey to understand the public's feelings about gene editing for newborns that would give them a reduced risk … Though they found some enthusiasm among the public about gene editing, they also found that about two-thirds of U.S. … … Germline Genome Editing, Gene Editing, DNA Editing, Gene Therapy, Genetic Disorder, Genetic Disease, CRISPR-Cas9, …
News Release
Researchers are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall.
… overall. … Precision medicine, drug prescribing, drug therapy, Vence Bonham, longitudinal drug studies, drug …
The Genomics Landscape
In the April 2020 edition of The Genomics Landscape, NHGRI Director Eric Green provides an update on the final stage of the Genomics2020 strategic planning process; the NIH website for COVID-19 information, the Gene documentary debut on PBS and more.
… below, the two-part documentary, “Ken Burns Presents The Gene: An Intimate History ,” will debut on PBS stations on … with the new PBS documentary, “Ken Burns Presents The Gene: An Intimate History ,” based on the book by Siddhartha … begins Genomic study points to natural origin of COVID-19 Gene mutation enhances cognitive flexibility in mice, NIH …
About Genomics
The Human Genome Project was an inward voyage of discovery led by an international team of researchers looking to sequence and map all the genes of our species.
Policy Issues
In June 2013, the Supreme Court determined that DNA in its natural form cannot be patented.
… discoveries. Since then, the core of the debate over gene patents has been whether or not the discovery of a gene or sequence of DNA rises to the level of invention … art to which said subject matter pertains." In the case of gene patents, critics have pointed out that such patents fail …