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Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… Liu's research over the years has been the mechanism of leukemia development at the molecular level, using genetic … a common chromosome abnormality in human acute myeloid leukemia. Using animal models, Dr. Liu has illustrated the importance of CBFB-MYH11 for leukemia development, and how this fusion gene works. His …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… has been linked to a range of diseases, including leukemia, lymphomas, and other types of cancer, but these …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… researchers identify potential drug targets, markers for leukemia risk  (2013)  Study reveals genomic similarities …  Researchers discover key mutation in acute myeloid leukemia  (2010)  The Cancer Genome Atlas Identifies …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… changes that lead to certain blood cancers, such as leukemia. Although Dr. Liu acknowledged that the zebrafish is not a proven model for leukemia, its transparent embryos develop in the water away …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… mechanisms across multiple subtypes of acute myeloid leukemia. In 2012, Dr. Heuston joined the laboratory of Dr. …
Staff
Dr. Raman Sood is an associate investigator in the Translational and Functional Genomics Branch and director of the Zebrafish Core at the National Human Genome Research Institute.
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… that lead to leukemogenesis, particularly acute myeloid leukemia involving mutations or chromosomal rearrangements of … For studies aimed at understanding the process of leukemia development in patients with chromosomal … t(8:21) identifies patterns of clonal evolution in relapse leukemia . Leukemia 30: 501-504. 2016. Carrington B, Varshney …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… non-coding sequence variation associated with pediatric leukemia. We plan to dissect non-coding regulatory elements … genes and describe their function in hematopoiesis and leukemia. Tychele Turner, Washington University in St. Louis …
Staff
Dr. Jennifer Troyer is the director of NHGRI's Division of Extramural Operations.
… Johnson WE, O'Brien SJ. Genetic characterization of feline leukemia virus from Florida panthers. Emerg Infect Dis, …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Office of Scientific Core Facilities.
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… V., Rai, K. R., Ferrarini, M., et al. Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and …