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15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… diagnosed with a blood cancer called acute lymphoblastic leukemia (or ALL) in 2003, when he was in his fourth year of … This led him to specialize in treating patients with leukemia, and studying the disease in the laboratory. While … better results by Monday. After a number of weeks, the leukemia cells were no longer detectable in his blood, …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… has been linked to a range of diseases, including leukemia, lymphomas, and other types of cancer, but these …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… researchers identify potential drug targets, markers for leukemia risk  (2013)  Study reveals genomic similarities …  Researchers discover key mutation in acute myeloid leukemia  (2010)  The Cancer Genome Atlas Identifies …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… (Purinethol) to patients with acute lymphoblastic leukemia. Some people have a genetic variant that interferes … of the treatment options for childhood acute lymphoblastic leukemia [cancer.gov] is stem cell transplantation therapy. …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… changes that lead to certain blood cancers, such as leukemia. Although Dr. Liu acknowledged that the zebrafish is not a proven model for leukemia, its transparent embryos develop in the water away …
For Patients and Families
​Genetic research is creating new ways for people to take action and prevent disease and new ways to treat disease through personalized medicine.​ ​
… in tumors. Children with a common type of childhood leukemia can be tested to find the right doses of …
For Patients and Families
​Pharmacogenomics combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.​
… (Purinethol) to patients with acute lymphoblastic leukemia. Some people have a genetic variant that interferes …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… designed to treat a blood cancer called chronic myeloid leukemia (CML). CML occurs because of a single genetic glitch …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… to serious problems. For example, in humans, one type of leukemia and some other cancers are caused by defective …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… non-coding sequence variation associated with pediatric leukemia. We plan to dissect non-coding regulatory elements … genes and describe their function in hematopoiesis and leukemia. Tychele Turner, Washington University in St. Louis …