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NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… the aggressive, potentially life-threatening tumors from curable, less aggressive tumors. … Researchers with the National Human Genome Research … a specific genomic signature of some aggressive prostate tumors, which may help health care providers pinpoint …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer. … More than 10,000 Tumors Analyzed "This project is the culmination of more than … with unprecedented understanding of how, where and why tumors arise in humans, enabling better informed clinical …
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TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… examining the entire genomes of 50 of the 66 ChRCC tumors studied, a high number for a rare cancer. The study … DNA. This led researchers to discover that ChRCC tumors favor a different energy-generating process than that … in the mitochondria, the cell's energy supplier. … Kidney tumors, chromophobe renal cell carcinoma, ChRCC, The Cancer …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… around the gene known as ZNF154 that is unique to tumors." Dr. Elnitski is head of the Genomic Functional … identified the methylation mark using DNA taken from solid tumors. "No one in my group slept the night after that … methylation marks in the mixture. Knowing that tumors often shed DNA into the bloodstream, they calculated …
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Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… subtypes that will help clinicians determine which tumors are more aggressive and which are more likely to … in the two PTC types, allowing them to characterize tumors and determine both the pathway a tumor uses to send … therapies. The study also showed that BRAF -driven tumors have a broader range of genetic complexity than …
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… to explore therapies in defined sets of patients whose tumors have specific genomic abnormalities. Stomach cancers … complex statistical analyses of molecular data from 295 tumors. They used six molecular analysis platforms including … DNA sequencing, RNA sequencing, and protein arrays. Tumors in the first group, which represented 9 percent of the …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… Jeannine Mjoseth … Cancerous tumors are voracious. Once they have consumed all the oxygen … trials are focused on targeting genetic changes in tumors and helping to boost one's immune system to fight the …
FAQ
Questions and answers from the September 26, 2022, Multi-Omics for Health and Disease Consortium Pre-Application Webinar.
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… head and neck cancers, noticeably in oropharyngeal tumors, has created an even greater sense of urgency in the … behind the mouth. "We're uncovering differences between tumors with and without HPV infection, and these new data are … the study, researchers performed genomic analyses on 279 tumors - head and neck squamous cell carcinomas (HNSCC) - …