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Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… disease. … The studies highlight the data generated by the modENCODE Project and the ENCODE Project, both supported by … species, the model organism ENCyclopedia Of DNA Elements (modENCODE) Consortium studied how gene expression patterns … controlling access to DNA. Launched in 2007, the goal of modENCODE is to create a comprehensive catalog of functional …
Research Funding
NHGRI's programs and projects support research in one of six domains to advance the field of genomics and improve human health.
… Model Organism ENCyclopedia Of DNA Elements Project (modENCODE) Molecular Libraries Program (MLP) Newborn …
Staff
Dr. Elise Feingold is a scientific program manager in NHGRI's Division of Genome Sciences.
… MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB et al. (modENCODE Consortium) Comparative analysis of the … analysis of the Caenorhabditis elegans genome by the modENCODE project. Science. 2010 Dec 24;330(6012):1775-87. … doi: 10.1126/science.1196914. PMID: 21177976 modENCODE Consortium, Roy S, Ernst J, Kharchenko PV, …
Staff
Dr. Mike Pazin is a program director in the Division of Genome Sciences at the National Human Genome Research Institute.
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… Committee, the ENCODE project , Common Fund Epigenomics modENCODE , the Non-Coding Variants (NoVa) program , and the …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… programs such as ENCODE (Encyclopedia of DNA Elements) and modENCODE (model organism Encyclopedia of DNA Elements) have … to try to better understand how genomes function. In modENCODE, researchers found shared patterns of gene activity …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) aims to identify all functional elements in the human and mouse genomes.
… Publications .) The ENCODE Portal also hosts data from modENCODE  as well as data from the RoadMap Epigenomics … the C. elegans  and D. melanogaster  genomes under the modENCODE Project. In recognition of the need for new … Consortium Data Release Policy  (2014-present) ENCODE-modENCODE Consortia Data Release Policy  (2008-2014) ENCODE …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… of the C. elegans and D. melanogaster genomes by the modENCODE Project . Recognizing the need for new approaches, …
Fact Sheets
La genómica comparada es un campo de la investigación biológica en el que los investigadores usan una variedad de herramientas para comparar las secuencias del genoma completo de distintas especies. ​
… de los Elementos del ADN de organismos modelo (modENCODE), han comparado y contrastado el funcionamiento … tratar de entender mejor cómo funcionan los genomas. En modENCODE, los investigadores encontraron patrones …
File
… 9:e1001046, 2011 Science 306:636, 2004 5 ENCODE Timeline 6 modENCODE Publications • Worm/fly/human comparative analyses … Genome Research, Genome Biology and other journals 7 modENCODE Publications • Data and links to papers can be …
NHGRI Director
A list of videos featuring NHGRI Director Eric Green, M.D., Ph.D.
… Science Center, co-chaired the workshop. Insights from the modENCODE Project (Welcome and Opening Remarks) - June 20, … of model organisms and human biology: Insights from the modENCODE Project, at the Ruth L. Kirschstein Auditorium, …