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Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… A computer program looks for overlaps in the DNA sequences, using them to reassemble the fragments in their …
15 Ways Genomics Influences Our World
Advances in genomics are reducing the cost of genome sequencing by a million-fold.
… the DNA; (2) read the sequence; and (3) compare to other sequences. First they use chemical methods to purify, then, … improving the accuracy of the reference " human genome sequences " that everyone can use for comparing newly generated human genome sequences. Powerful new computer-based methods for analyzing …
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
Research Funding
Coordinates activities across the Genome Sequencing Program components
Fact Sheets
Estimated cost of sequencing the human genome over time since the Human Genome Project.
… aided by the availability of available 'reference' sequences of the human genome, which play an important role … driver of the costs associated with generating genome sequences relates to data quality. That quality is heavily … associated with high costs. In fact, most human genome sequences produced today are 'draft sequences' (sometimes …
Fact Sheets
Data used to estimate the cost of sequencing the human genome over time since the Human Genome Project.
Research Funding
Funded in 2016 to harmonize, access, and analyze the data produced by the sequencing centers.
News Release
The Clinical Sequencing Exploratory Research Consortium has offered an ethical framework to guide pediatricians in pursuing clinical sequencing studies.
Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… delay and metabolic diseases. Comparing the genome sequences of different types of animals and organisms, such …
News Release
Researchers, clinicians, and computational biologists meet to consider future opportunities for NHGRI's Genome Sequencing Program.