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News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… changes that lead to certain blood cancers, such as leukemia. Although Dr. Liu acknowledged that the zebrafish is not a proven model for leukemia, its transparent embryos develop in the water away …
Staff
Dr. Mo is an adjunct staff clinician in the Hematology Laboratory, Department of Laboratory Medicine in the NIH Clinical Center.
… of measurable residual disease in chronic lymphocytic leukemia using an artificial intelligence-assisted workflow . … S, Konoplev SN, Mo H , Liu W, et al. Acute promyelocytic leukemia: Immunophenotype and differential diagnosis by flow …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… mechanisms across multiple subtypes of acute myeloid leukemia. In 2012, Dr. Heuston joined the laboratory of Dr. …
Staff
Dr. Raman Sood is an associate investigator in the Translational and Functional Genomics Branch and director of the Zebrafish Core at the National Human Genome Research Institute.
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… that lead to leukemogenesis, particularly acute myeloid leukemia involving mutations or chromosomal rearrangements of … For studies aimed at understanding the process of leukemia development in patients with chromosomal … t(8:21) identifies patterns of clonal evolution in relapse leukemia . Leukemia 30: 501-504. 2016. Carrington B, Varshney …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… hope to develop new therapies to treat patients with leukemia using their own iPSCs. We encourage other …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… cancers, sarcomas, colon cancers, bladder cancers and leukemia. Future studies are looking towards detecting the …
For Patients and Families
​Genetic research is creating new ways for people to take action and prevent disease and new ways to treat disease through personalized medicine.​ ​
… in tumors. Children with a common type of childhood leukemia can be tested to find the right doses of …
File
… blood cancers such as myelodysplastic syndrome or leukemia. Newsletter 2 Genomic research team New additions to … with R U N X1 to increase a person’s risk of developing leukemia or make their disease more severe? Are there … mutations in R U N X1 that happened after they developed leukemia – this is a bit different than having germline R U N …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Layla received a gene editing treatment to help her fight leukemia, a type of cancer. These scientists did not use …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… designed to treat a blood cancer called chronic myeloid leukemia (CML). CML occurs because of a single genetic glitch …