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Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and progression. … The branch focuses …
Talking Glossary
El cáncer es una enfermedad en la que algunas células del cuerpo crecen fuera de control. Hay muchos tipos diferentes de cáncer, y cada uno comienza cuando una única célula adquiere un cambio genómico (o mutación) que le permite dividirse y multiplicarse sin control.
… que le permite dividirse y multiplicarse sin control. … Cancer is a disease in which some of the body’s cells grow uncontrollably. There are many different types of cancer, and each begins when a single cell acquires a genomic … and multiply unchecked. Additional mutations can cause the cancer to spread to other sites. Such mutations can be caused …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … diagnosis and treatment. … WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new …
Genetic Disorders
Colon cancer is a malignant tumor of the large intestine that affects both men and women.
… Colon cancer, a malignant tumor of the large intestine, affects … States, approximately 160,000 new cases of colorectal cancer are diagnosed each year. … Colon cancer, a malignant tumor of the large intestine, affects …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Kyle Davis … Receiving a cancer diagnosis can feel like losing control of everything. … its natural defenses, which can then lead to diseases like cancer," said Laura Elnitski, Ph.D., a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no … associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in 6 American men will develop prostate cancer …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… from over 10,000 tumors representing 33 types of cancer. … More than 10,000 Tumors Analyzed "This project is … Francis S. Collins, M.D., Ph.D. "This analysis provides cancer researchers with unprecedented understanding of how, … Human Genome Research Institute (NHGRI): NHGRI leads genomics research at the National Institutes of Health (NIH), …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… Communications and Public Liaison Branch … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical … senior investigator in the Translational and Functional Genomics Branch at NHGRI. In 2013, her research group …