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Educational Resources
Gene mapping is the process of establishing the locations of genes on the chromosomes.
… mapping is the process of establishing the locations of genes on the chromosomes. … Chromosomes, Linkage Analysis, … refers to the process of determining the location of genes on chromosomes. Today, the most efficient approach for gene mapping involves sequencing a genome and then using computer programs to analyze the sequence to …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… it encodes is not produced or does not function properly, and as a result, uncontrolled cell division may occur. Such …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… be thought of as an “on/off switch” to control when and where RNA molecules and proteins are made and as a … and cell types. The RNA and protein products of many genes serve to regulate the expression of other genes. Where, when, and how much a gene is expressed can also …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National … effective than other techniques at homing in on target genes and inserting or deleting specific sequences. The study …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
… of canine genomics, sport hunting dogs are super athletes and terriers are plucky supermodels. National Human Genome … researchers reached this conclusion after identifying 59 genes or gene regions linked to canine athletics, including … moustache and eyebrows. Gene variants associated with autism-like behaviors, hyperactivity and panic responses in …
Talking Glossary
La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y el entorno físico y social.
… Interacción genes-ambiente … La interacción genes–ambiente se refiere a interrelación de los genes (y en … interaction refers to the interplay of genes (and, more broadly, genome function) and the physical and
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… cell fates or cell states. They use the gene expression and functional element data to construct gene regulatory … from one physiologic state to another. They derive and test predictions from the models, to determine the … data to understand what elements are controlling what genes, in what cell types. The ability to make accurate …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… have inherited mutations in certain cancer-susceptibility genes have a lifetime risk of cancer that is significantly …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… at NIH's National Human Genome Research Institute (NHGRI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, was published Oct. 26, 2016, in the … Human Molecular Genetics . Niemann-Pick disease is a rare and fatal disorder of the central nervous system (the brain …