Search Results
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
… The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch (MCIDGB) studies the genomic and social determinants of complex diseases. … scleroderma and podoconiosis). MCIDGB researchers analyze genomic data to document and interpret the non-random distribution of …
CRGGH is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch.
… newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch (MCIDGB). … Dan Kastner, this reorganization was conducted, in part, to facilitate new "scientific synergies." These synergies … Senior Investigator, Charles Rotimi, has been selected to serve as the MCIDGB Branch Chief, a major scientific …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… Complex Disease … A complex disease is caused by the interaction of multiple genes and … Genes, Cancer, Heart Disease, Gene-environment Interactions … a disorder that results from the contributions of multiple genomic variants and genes in conjunction with significant …
For Patients and Families
A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United States at any given time.
… A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United … Altogether, rare diseases affect an estimated 25 million to 30 million Americans. … Altogether, rare diseases affect an estimated 25 million to 30 million Americans. …
Research at NHGRI
NHGRI center focused on computationally intensive approaches to analyze large-scale genomic data and identifying genetic contributions to human disease.
… and application of computationally intensive approaches to analyze large-scale genetic and genomic data, with a particular focus on identifying genetic contributions to human disease. … to untangle the complexities of the genome and uncover genomic associations with health and disease. Members of the …
Profile
Jim Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics.
… human genome sequence was finished just before I moved to NHGRI in 2003. Seeing the whole progress, from the very … involved in several other big projects looking at human genomic variation. Early in the Human Genome Project, even … those variants and how they contribute to human health and disease.  Another big one for me was working with Svante …
Clinical Research
This study explores how microbes, such as bacteria and fungi, contribute to a very common skin condition called Atopic Dermatitis, known as eczema.
… The study is trying to determine how microbes, such as bacteria and fungi, contribute to a very common skin condition called Atopic Dermatitis (AD), also … for development of more effective treatments for the disease. … We invite you or your child to join a research study of both healthy volunteers and …
The Informed Consent Resource
Explore the basic elements of informed consent that are required by the Common Rule and that are relevant to genomics.
… elements of informed consent that are required by the Common Rule (45 CFR 46, Subpart A) and that are relevant to genomics. It also provides sample language that can be … topics such as a brief description of the underlying genomic science, the study design, the diseases(s) or …
News Release
Six new grants will support researchers for new computational approaches to search millions of genomic variants for disease susceptibility.
… Institutes of Health (NIH) will support researchers to develop new computational approaches for searching among millions of genomic variants to find those that make a difference in disease susceptibility or in other traits. The awards are for … people with and without a disease are compared to find the genomic regions containing variants that affect disease risk. …
Staff
Dr. ​Adam Felsenfeld is a program director in the Division of Genome Sciences at the National Human Genome Research Institute.​
… and specific responsibility for the NHGRI Centers for Common Disease Genomics program and the GSP Analysis Centers. … and coordinating new sequencing projects, policy related to deposition and release of human sequence data, and … and is coordinator for the Centers of Excellence in Genomic Sciences Program. Dr. Felsenfeld is also involved …