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News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… large numbers of genotypes (an individual's collection of genes). Until now, it has been difficult for researchers to … interest and investigate the health consequences of their genes and gene variants. … Reversing a Long-Standing Paradigm … will allow them to recall genotyped people and examine the genes and gene variants' influence on their phenotypes, an …
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… of a trait that results from the interplay between genes and the environment. … Genes, Environmental Factors, Genetics, DNA … Gene–environment interaction refers to the interplay of genes (and, more broadly, genome function) and the physical …
Educational Resources
A gene pool is the total genetic diversity found within a population or a species.
… within a population or a species. … Genetic Diversity, Genes, Extinction, Population Genetics … A gene pool refers to the combination of all the genes (including alleles) present in a reproducing population …
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… by improving our knowledge of the relationship between genes, social factors, the environment and cardiovascular …
Educational Resources
Gene mapping is the process of establishing the locations of genes on the chromosomes.
… mapping is the process of establishing the locations of genes on the chromosomes. … Chromosomes, Linkage Analysis, … refers to the process of determining the location of genes on chromosomes. Today, the most efficient approach for … to analyze the sequence to identify the location of genes. … Gene mapping is the process of establishing the …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… and cell types. The RNA and protein products of many genes serve to regulate the expression of other genes. Where, when, and how much a gene is expressed can also …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… of gene function and the identification of disease genes in humans, according to scientists at the National … effective than other techniques at homing in on target genes and inserting or deleting specific sequences. The study … team's method is the zebrafish. The zebrafish and the mouse are the most commonly studied vertebrate laboratory …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… data to understand what elements are controlling what genes, in what cell types. The ability to make accurate … Post-transcriptional response to pathogens, primary mouse macrophages Christina Leslie, Ph.D. and Alexander … Populations In Inflammation In vivo inflammation model, mouse T helper cells Jeremy Luban, M.D. and Manuel Garber, …