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Data used to estimate the cost of sequencing the human genome over time since the Human Genome Project.
… Institute (NHGRI) has tracked the costs associated with DNA sequencing performed at the sequencing centers funded by the … as an important benchmark for assessing improvements in DNA sequencing technologies and for establishing the DNA … relative to two metrics: (1) "Cost per Megabase of DNA Sequence" - the cost of determining one megabase (Mb; a …
Talking Glossary
While some sequencing technologies produce reads that are only a few hundred nucleotides long, some methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.”
… Long-Read DNA Sequencing … While some sequencing technologies produce reads that are only a few … of thousands of nucleotides long, known as “long-read DNA sequencing.” … DNA sequencing technologies determine the order of the base pairs … of thousands of nucleotides long, known as “long-read DNA sequencing.” …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… Recombinant DNA Technology … Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest. … Cell, Deoxyribonucleic Acid (DNA), Enzyme, Gene Expression, Restriction Enzyme, Vector … Recombinant DNA technology involves using enzymes and various laboratory …
Fact Sheets
A DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes.
… The DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes. … that a mutation - or alteration - in a particular gene's DNA may contribute to a certain disease. However, it can be … surface, each chip contains thousands of short, synthetic, single-stranded DNA sequences, which together add up to the …
Talking Glossary
Chromosomes are threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information from cell to cell.
… Chromosomes are threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information from cell to … Chromosomes are threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information …
Educational Resources
DNA fingerprinting is a laboratory technique used to establish a link between biological evidence and a suspect in a criminal investigation.
… DNA Fingerprinting … DNA fingerprinting is a laboratory technique used to … DNA Fingerprinting, Criminal Investigation, Forensics, DNA Sequence, Paternity Test … DNA fingerprinting is a laboratory technique used to … on the nucleotide sequences of certain regions of human DNA that are unique to individuals. DNA fingerprinting is …
Educational Resources
A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome.
… A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome. … DNA Sequences, DNA Mapping, Chromosomes … studies; derived from the word “contiguous”) is a set of DNA segments or sequences that overlap in a way that provides …
Educational Resources
DNA replication is the process by which a molecule of DNA is duplicated.
… DNA Replication … DNA replication is the process by which a molecule of DNA is duplicated. … DNA, Cell Division, Cell Biology … DNA replication is the process by which the genome’s DNA is copied in cells. Before a cell divides, it must first … DNA replication is the process by which a molecule of DNA is duplicated. …
News Release
NHGRI-funded CSER investigators and colleagues point to need for greater evidence that DNA sequencing helps patients.
… In the nearly four years since its launch, the Clinical Sequencing Exploratory Research (CSER) program has made … have discovered genomic variants - differences in the DNA code - that could contribute to disease; improved the analysis and interpretation of DNA sequencing results; and provided new insights into the …
Educational Resources
Non-coding DNA corresponds to the portions of an organism’s genome that do not code for amino acids, the building blocks of proteins.
… Non-Coding DNA … Non-coding DNA corresponds to the portions of an organism’s genome that … DNA Sequence, Gene Expression, Chromosome, Non-coding DNA, Junk DNA, Genetic Code … Non-coding DNA corresponds to the portions of an organism’s genome that … acids, the building blocks of proteins. Some non-coding DNA sequences are known to serve functional roles, such as in …