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News Release
National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study may inform the development of treatments for hearing loss in humans.
… Study shows the role of transcription factors in facilitating cell regeneration …   … of proteins that can switch genes on and off, known as transcription factors. To properly identify which transcription factors were at play, the researchers first had …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… of variants on gene expression, chromatin organization and transcription factor binding as cells undergo …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
File
… presenting this, I said, "Don't be surprised." You know, transcription from this perspective is, you know, is … there as one of these reproducible events. And not only transcription as in making RNA, but the passage of the …
Educational Resources
An intron is a portion of a gene that does not code for amino acids.
… not remain in the final mature mRNA molecule following transcription of that gene and does not code for amino acids …
News Release
NHGRI awards $6.7 million in new research grants to develop DNA sequencing technologies that are more sensitive, faster, cheaper and more accurate.
Media Availability
New research provides a better understanding of some of the genetic and cellular changes in pathways and processes involved in Autism Spectrum Disorder.
… off, and the formation of neural connections in the brain. Transcription. Instructions embedded in genes must be … or read, to build proteins, the workhorse of the cell. Transcription mistakes can affect a wide range of important …
Fact Sheet
Genomic research has been central to understanding and combating the SARS-CoV-2 (COVID-19) pandemic.
… RNA to double-stranded DNA in a process called reverse transcription. The two DNA template strands are then …
Genomics Teaching Tool
An activity that demonstrates how DNA can be isolated from a strawberry using common household items.