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News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… studies on obesity using a GWAS have been conducted with populations of European ancestry; these studies wouldn't have … his colleagues plan to replicate these findings in more populations and conduct experiments using cell lines and … studies of DNA sequencing of this gene in different human populations with the hope of identifying other genomic …
Educational Resources
A gene pool is the total genetic diversity found within a population or a species.
… Inbreeding contributes to a smaller gene pool, making populations or species less able to adapt and survive when …
Policy Issues
NHGRI wants to ensure that all populations benefit from the advances of genomics research.
… Genome Research Institute (NHGRI) wants to ensure that all populations benefit from the advances of genomics research, … and Minority Health Resources HHS and NIH Resources American Indian and Alaska Native Communities and Genetics Research …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… Tayo Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of … and Transferability of Polygenic Scores Across Diverse Populations: A Focus on South Asians Mayo Clinic, Rochester, … Kullo*, Daniel Schaid Polygenic Risk of Disease in Populations of Diverse Ancestry UNC-Chapel Hill Yun Li*, …
Educational Resources
The founder effect is the reduction in genetic variation that results when a small subset of a large population is used to establish a new colony.
FAQ
On October 10, 2024, NHGRI hosted a pre-application webinar for the Population Genomic Screening in Primary Care NOFOs: RFA-HG-24-021, RFA-HG-24-022, and RFA-HG-24-023. These FAQs contain questions answered during that webinar.
… The NOFO requires the inclusion of “ Health disparities populations ” which refers to racial and ethnic minority … care and should consider the impact of their patient populations (typically younger women) on the overall … by the Review Branch at NHGRI. “Health disparities populations” - how should we define "people with …
Educational Resources
Genetic epidemiology is a relatively new medical discipline that seeks to understand how genetic factors interact with the environment in the context of disease in populations.
… interact with the environment in the context of disease in populations. … Genetic Epidemiology, Healthcare, Medicine, … and the multifactorial causes of genetic diseases in populations. … Genetic epidemiology is a relatively new … interact with the environment in the context of disease in populations. … Educational Resources …
Event
Several NIH Institutes, Offices and Centers partnered to host a two-day virtual workshop on May 28-29, 2024, to further explore the recommendations from the National Academies of Sciences, Engineering and Medicine (NASEM) 2023 report, Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field, with regards to legacy genomic data.
The Genomics Landscape
In May 4, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., details a report released by the National Academies of Science, Engineering, and Medicine, that provided a series of recommendations for using population descriptors in future genetics and genomics studies.
… scientific progress, the terms used to describe human populations have remained stuck in the past. Genetics and … reproducibility of research studies and ensure that all populations benefit from genomic advances. The scientific and …
News Release
NIH-backed African scientists are engaged in a global research endeavor to understand the genetic basis of disease in all populations.
… endeavor to understand the genetic basis of disease in all populations. But this can only be done by including populations that are the most genetically diverse. … A Global Research Endeavor Studies have shown that African populations contain the oldest and most diverse set of human …