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- Ethical, Legal and Social Implications (ELSI) Research Program6
- Genomics-Enabled Learning Health Systems (gLHS)2
- Genetic Architecture of Complex Traits1
- Genome Technology Program5
- Human Genome Reference Program (HGRP)2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Encyclopedia of DNA Elements (ENCODE) Project1
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- Genomic Innovator Awards2
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)3
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
- Developmental Genotype-Tissue Expression (dGTEx)1
- Multi-Omics for Health and Disease (Multi-Omics)1
Genetic Disorders
Colon cancer is a malignant tumor of the large intestine that affects both men and women.
… Colon cancer, a malignant tumor of the large intestine, affects … States, approximately 160,000 new cases of colorectal cancer are diagnosed each year. … Colon cancer, a malignant tumor of the large intestine, affects …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Kyle Davis … Receiving a cancer diagnosis can feel like losing control of everything. … its natural defenses, which can then lead to diseases like cancer," said Laura Elnitski, Ph.D., a senior investigator in … and Functional Genomics Branch at the National Human Genome Research Institute (NHGRI). "In a way, it's like …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no … and Functional Genomics Branch at the National Human Genome Research Institute, and their collaborators studied 10 …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in 6 American men will develop prostate cancer …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research Institute (NHGRI) researchers and their … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical … Division of Intramural Research at NIH's National Human Genome Research Institute (NHGRI). "It's a technical …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… Bruce Agnew … For many cancer patients and their doctors, the deadliest enemy is metastasis - the migration of cancer cells from the original tumor to other places in the … and Shawn Burgess, Ph.D., both of the National Human Genome Research Institute (NHGRI), and their colleagues wrote …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated … Program; Heidi Parker, Ph.D., of the National Human Genome Research Institute (NHGRI); and Elaine Ostrander, …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… Steven Benowitz … An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because … Canine transmissible venereal tumor, or CTVT, spreads when cancer cells move from one dog to the other during sexual … the dog tumor genomes, researchers at the National Human Genome Research Institute (NHGRI), part of the National …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH. … The Bell laboratory is … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify …