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A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… designed to treat a blood cancer called chronic myeloid leukemia (CML). CML occurs because of a single genetic glitch …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… to serious problems. For example, in humans, one type of leukemia and some other cancers are caused by defective …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… non-coding sequence variation associated with pediatric leukemia. We plan to dissect non-coding regulatory elements … genes and describe their function in hematopoiesis and leukemia. Tychele Turner, Washington University in St. Louis …
Staff
Dr. Jennifer Troyer is the director of NHGRI's Division of Extramural Operations.
… Johnson WE, O'Brien SJ. Genetic characterization of feline leukemia virus from Florida panthers. Emerg Infect Dis, …
Genetic Disorders
Severe Combined Immunodeficiency is a severe, genetic condition of the immune system.
… a French gene-therapy experiment had developed a type of leukemia. It was soon discovered that the mechanism used to …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Office of Scientific Core Facilities.
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… V., Rai, K. R., Ferrarini, M., et al. Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… Foundation Eukaryotic Genetics Panel and has served on the Leukemia and Lymphoma Society (LLS) Career Development Award …
Staff
Dr. Pamela Schwartzberg is a adjunct investigator in NHGRI's Genetic Disease Research Branch.
… involving tyrosine kinases as a special fellow of the Leukemia and Lymphoma Society (in collaboration with Michael …
Staff
Dr. Francis Collins is a senior investigator in Center for Precision Health Research.
… beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia . Science, 261, 1041-1044. 1993. Ballester R, …