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News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Receiving a cancer diagnosis can feel like losing control of everything. In the wake of such a diagnosis, patients, family and friends … but in other cases they are elusive. Without information, the patient may decide to treat a benign tumor with harsh … from each other - either in different organs or within the same organ - can yield useful clues about prognosis and …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from … their lifetime. At this time, more than 2 million men in the United States who have had prostate cancer at some point … The prostate is a small gland shaped like a walnut that is in the center of a man's body within the pelvis. The prostate …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… For a patient with cancer, two of the most important words in the oncologist's lexicon begin with the letter "r": remission … do some patients stay in remission, while others see their cancer return? To get a better idea of who will be more … whose rules are constantly being written and rewritten by the cancer's rogue cells. Untangling the genetic influences …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research Institute (NHGRI) researchers and their … Largest Study of Its Kind Endometrial cancer is the most commonly diagnosed gynecological cancer with more …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation … signature may be present in many more types of cancer. The specific signature results from a chemical modification of DNA called methylation, which can control the expression of genes like a dimmer on a light switch. …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… For many cancer patients and their doctors, the deadliest enemy is metastasis - the migration of cancer cells from the original tumor to … zebrafish as a live animal model of metastasis - offering cancer researchers a new, potentially more accurate way to … for drugs and to identify new genetic targets against the disease. Current screening of possible anti-metastasis …
News Release
NHGRI appointed Carolyn Hutter, Ph.D., director of the Division of Genome Sciences, which researches human genome function in health and disease.
… The National Human Genome Research Institute (NHGRI) has appointed Carolyn Hutter, Ph.D., the director of the Division of Genome Sciences - the NHGRI division that leads research … Dr. Hutter comes to the position with extensive experience leading large-scale …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… Over the years, domestic dogs have figured in medical … our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated … in multiple human cancers, a team of scientists from the National Institutes of Health, Purdue University in West …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because of the similarities in the dog and human immune systems - has baffled researchers … By comparing the genomes of 186 healthy dogs from a wide variety of … immune systems from detecting and fending off invading cancer cells. They reported their results online July 31, …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH. … The Bell laboratory is seeking a highly motivated … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify …