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… ministudy@nih.gov National Human Genome Research Institute Acute Infection in Mitochondrial Disease Why are we doing … Research Nurse and study coordinator, at 301-451-9145. … Acute Infection in Mitochondrial Disease Flyer …
Genetic Disorders
Severe Combined Immunodeficiency is a severe, genetic condition of the immune system.
… to a variety of infections, including ear infections (acute otitis media), pneumonia or bronchitis, oral thrush (a … a French gene-therapy experiment had developed a type of leukemia. It was soon discovered that the mechanism used to …
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… blood cancers such as myelodysplastic syndrome or leukemia. Newsletter 2 Genomic research team New additions to … This meant restricting patients to those who are having acute interventions performed such as bone marrow transplant, … with R U N X1 to increase a person’s risk of developing leukemia or make their disease more severe? Are there …
News Release
NHGRI researchers have discovered a new inflammatory disorder called vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic syndrome (VEXAS), which is caused by mutations in the UBA1 gene.
… and vacuoles (unusual cavity-like structures) in myeloid cells. The scientists reported their findings in the … that the mosaicism was indeed present in the patients’ myeloid cells, which are responsible for systemic … and vacuoles (unusual cavity-like structures) in the myeloid cells. Out of the combined 25 individuals, …
Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… and sickle cell disease) and acquired disorders (e.g., leukemia) have been treated with gene therapy. … Educational …
Profile
David Bodine, founder of the Hematopoiesis Section and chief of the Genetics and Molecular Biology Branch, advanced the fields of gene therapy and hematology in his 38 years at the NIH. Now, he plans to continue his contributions to science as an emeritus and through training the next generation of scientists.
… and ask, “Why does that one stem cell go nuts and become leukemia? Is it because of where it is, or is it because of … If you could then change the microenvironment and cure leukemia that way, it'd be a lot better than chemotherapy. … …
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… ministudy@nih.gov National Human Genome Research Institute Acute Infection in Mitochondrial Disease Why are we doing … Research Nurse and study coordinator, at 301-451-9145. … Acute Infection in Mitochondrial Disease Study Flyer - …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… has been linked to a range of diseases, including leukemia, lymphomas, and other types of cancer, but these …
Staff
Dr. Gordon-Lipkin is a researcher and child neurologist with expertise in neurodevelopmental disabilities in the Metabolism, Infection and Immunity (MINI) Section.
… conditions including autoimmune encephalitis, acute flaccid myelitis, and multiple sclerosis. Her current … neuroimaging, and functional profiles in children with acute flaccid myelitis at acute and convalescent stages of disease .  Dev Med Child …
The Genomics Landscape
In the November 2024 issue of The Genomics Landscape, NHGRI Director Eric Green spotlights the History of Genomics Program, which has long worked to make various materials related to the history of genomics accessible to the public.
… clinical trial will test precision medicine treatments for myeloid cancers Notable accomplishments in genomic medicine …