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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… subtypes that will help clinicians determine which tumors are more aggressive and which are more likely to … in the two PTC types, allowing them to characterize tumors and determine both the pathway a tumor uses to send … therapies. The study also showed that BRAF -driven tumors have a broader range of genetic complexity than …
Educational Resources
A carcinogen is an agent with the capacity to cause cancer in humans.
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… to explore therapies in defined sets of patients whose tumors have specific genomic abnormalities. Stomach cancers … complex statistical analyses of molecular data from 295 tumors. They used six molecular analysis platforms including … DNA sequencing, RNA sequencing, and protein arrays. Tumors in the first group, which represented 9 percent of the …
Educational Resources
An oncogene is a mutated gene that contributes to the development of a cancer.
Staff
Dr. Douglas Stewart is an associate investigator in NHGRI's Center for Precision Health Research.
… increases the risk of various benign and malignant tumors in affected individuals. His research group … among a variety of novel NF1 phenotypes, including glomus tumors, gastrointestinal stromal tumors and pulmonary hypertension. Dr. Stewart's group is …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
Genetic Disorders
Klinefelter syndrome is a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility.
Educational Resources
Huntington's disease is an inherited disease characterized by the progressive loss of brain and muscle function.
… inherited disease characterized by the progressive loss of brain and muscle function. … Huntington's Disease, Genetic … inherited disorder associated with the progressive loss of brain and muscle function. Symptoms usually develop during …