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Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… can recognize and attack the virus before it can infect healthy cells or cause illness.   … Traditional vaccines … vaccines authorized for use in the United States by the Food and Drug Administration (FDA) are mRNA vaccines. … Fact …
News Release
Mothers may be able to reduce guilt over their children's inherited obesity guilt by being more careful in the future about their children's diet.
… behavioral underpinnings like willingness to exercise and food preferences that contribute to obesity. "A lot of genes … asked to choose a meal for their children in a virtual food "buffet" in NIH's Immersive Virtual Environment Testing … that included healthful, less healthful and unhealthful choices. The mothers who chose healthier foods felt less …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… cell to move. … For your body to develop properly and stay healthy, many things must work together at many different … injury, infection, stress or even the presence or lack of food. To react and adjust to these cues, cells send and … researchers may compare certain biological pathways in a healthy person to the same pathways in a person with a …
News Release
Researchers funded by NIH have completed a detailed atlas documenting stretches of human DNA that influence gene expression.
… genomic variation leads to biological differences, like healthy and diseased states, across human tissues and cell … in gene expression that underlie differences among healthy individuals. Although the GTEx project has officially …
FAQ
Addressing the COVID-19 pandemic and what it means to the pediatric mitochondrial disease community.
… in the cell called mitochondria and extracts energy from food and other sources. Because mitochondria are found in … result from infection. Our goal is to keep these children healthy and infection-free. Usually, children and their … part of keeping children with mitochondrial disease healthy. Although the COVID-19 vaccines have yet to be …
Fact Sheet
Several regulations and policies stipulate the information that must be given to research participants prior to their enrolling in a study.
… private information or identifiable biospecimens."  Food and Drug Administration (FDA) regulations require …
Genetic Disorders
Familial hypercholesterolemia is an inherited condition causing increased low density lipoprotein cholesterol at birth and heart attacks at an early age.
… to make hormones, vitamin D, and substances that help with food digestion. However, if too much cholesterol is present …
For Patients and Families
​Clinical research is research conducted with human subjects, or material of human origin, in which the researcher directly interacts with human subjects.
… (changes in gene sequence) that caused the normal, healthy cells to become cancerous, and may help doctors … today may help other doctors in the future screen their healthy patients before they ever develop cancer. … All … (See: Informed Consent for Genomics Research ). The Food and Drug Administration (FDA) provides details about …
Fact Sheet
Pharmacogenomics is a growing area of genomic medicine that uses a person’s genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.
… guidelines are open-access and freely available. The U.S. Food and Drug Administration (FDA) also incorporates …
Genetic Disorders
Trimethylaminuria is a metabolic condition in which an individual is not able to convert trimethylamine into a compound called trimethylamine N-oxide.
… odor, individuals with this condition typically appear healthy. The condition seems to be more common in women than … is possible for people with this condition to live normal, healthy lives. The following are some ways a person with … Recommended intake is 30-40mg taken 3-5 times per day with food. Avoiding factors that promote sweating, such as …