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- Ethical, Legal and Social Implications (ELSI) Research Program1
- Genome Technology Program3
- Impact of Genomic Variation on Function (IGVF) Consortium1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
15 Ways Genomics Influences Our World
Genomics is advancing the study of individual and communities of microbes.
… microbial genomics, what else can we do? The field of synthetic biology  has emerged directly from advances in DNA … Rampant Transfer Of Genes, Human Microbiome Project, Synthetic Biology … Genomics is advancing the study of …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Office of Scientific Core Facilities.
… in 1993. At the NHGRI, Dr. Elkahloun started applying large scale screening methods to identify genes associated … Office of Scientific Core Facilities. … Abdel Elkahloun, large-scale screening methods, microarray technology, …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… team and our patients, extending to humanity at large. And that trust, in turn, is built upon the scientific … Common Fund project, has completed its goal of creating a large-scale, systematically generated molecular and cellular … the impressive usage statistics above, several small and large pharmaceutical companies (e.g., AstraZeneca, Genentech, …
Event
The NHGRI Center for Precision Health Research sponsors a monthly series of talks by intramural and special guest speakers on research relevant to the use of genomic data and large-scale electronic health record information to improve health.
… on research relevant to the use of genomic data and large-scale electronic health record information to improve … on research relevant to the use of genomic data and large-scale electronic health record information to improve … on research relevant to the use of genomic data and large-scale electronic health record information to improve …
News Release
Researchers have now identified and catalogued more species - nearly 200 new bacteria and thousands of viruses - that reside on the human skin than has ever been possible, largely due to advances in bioinformatics and laboratory techniques.
Jobs at NHGRI
NHGRI is seeking a postdoc to join the Systems Biology and Genome Engineering Section in Bethesda, Maryland.
… methods. This includes harnessing the strengths of CRISPR, large scale oligo synthesis, and yeast genetics. Research in … Engineering Section, in Bethesda, Maryland.​ … CRISPR, Large Scale Oligo Synthesis, Yeast Genetics, Postdoctoral …
The Genomics Landscape
In the May 2020 edition of The Genomics Landscape, NHGRI Director Eric Green details how NIH is ramping up research on COVID-19; NHGRI's expansion of its Genome Technology Program; and the the DiY Genome: Unlocking Life's Code exhibition toolkit.
… that will support investigators developing novel synthetic nucleic acid technologies and a coordinating … have now been published. The first component, the Novel Synthetic Nucleic Acid Technology Development FOA, is … into various types of spaces – schools, community centers, libraries, cafés, hospitals, transit hubs, museums, science …
News Release
CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and triglycerides.
… Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × … Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × … Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
… variants associated with blood lipid levels. … In a large-scale study of people from diverse ancestries, … a powerful tool for studying risk of heart disease … In a large-scale study of people from diverse ancestries, … levels, a major risk factor for heart disease. … In a large-scale study of people from diverse ancestries, …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… 1999 2002  … cDNA:  cDNA stands for complementary DNA, a synthetic type of DNA generated from messenger RNA, or mRNA, … creating a collection of cDNAs, or a cDNA library. These libraries are important to scientists because they consist of … Microarray:  Microarrays are devices used in many types of large-scale genetic analysis. They can be used to study how …