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NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
… for a variety of health conditions, such as breast cancer, obesity and heart diseases. Although such risk predictions …
Research at NHGRI
CRGGH facilitates understanding of the relationship between genetic variation and population differences in disease distribution to inform health disparities.
… the pathobiology of metabolic disorders, including obesity, hypertension, diabetes, dyslipidemia, and kidney …
Staff
Dr. Charles Rotimi is the scientific director of and NIH Distinguished Investigator in the Division of Intramural Research. He also serves as the director of the Center for Research on Genomics and Global Health (CRGGH).
… area include the mapping of variation in the FTO gene for obesity, characterizing the role of interleukin (IL)-6, IL-10, and IL-1RA in obesity and insulin resistance in African Americans (AA), and … In contrast to the increased prevalence of HTN, T2D and obesity observed with increasing westernization, the …
For Teachers
A microbiome is all of the genetic material found in a microbe, such as a bacterium, fungal cell or virus.
… not seem to have anything to do with bacteria, including obesity and diabetes. Explore the Human Microbiome By …
News Release
NHGRI researchers and colleagues are calling for health disparities research that focuses on the microbiome.
… alter the gut microbiome and increase risk for developing obesity later in life, according to the perspective. This …
News Release
Researchers have discovered that FGF21 is elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia.
… on more common disorders such as fatty liver disease, obesity and diabetes by uncovering similarities in how MMA …
Staff
Dr. Rongling Li is an epidemiologist and program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
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… U Peters. Genetic risk factors for body mass index and obesity in an ethnically diverse population: results from the … architecture using genomics and epidemiology (PAGE) study. Obesity , 21:835. 2013. [ PubMed ] MD Ritchie, JC Denny, RL … Health ABC study. Shorter telomeres are associated with obesity and weight gain in the elderly. International Journal …
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… Digestive and Kidney Diseases, NIH Project: Genetics of Obesity, Diabetes, and Heart Disease in African Dias pora … School of Medicine Project: Genetics of Hypertension and Obesity in Populations of African Ancestry Profess or Barry …
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… Exome / Genome Sequencing Obesity Study Consent Form …
Diversity Center
Meharry Medical College establishes a Diversity Center for Genome Research (DCGR) that will narrow inequitable representation gaps for underrepresented, disadvantaged minority by realizing their vision to promote African ancestry genomic research through infrastructure building and the formation of basic, clinical, and computational science research teams that are inclusive, interdisciplinary, and community-engaged.
… such as cancer, hypertension, kidney disease, diabetes, obesity, neurodegenerative diseases and psychiatric …