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News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… A repurposed cancer drug appears to reduce the severity of lesions and … disease. The drug, miransertib, was well tolerated, even in children, according to a National Institutes of Health … and collaborators published the findings Feb. 21, 2019, in the American Journal of Human Genetics . …
Talking Glossary
La hibridación in situ es una técnica de laboratorio empleada para localizar una secuencia de ADN o ARN en una muestra biológica.
… Hibridación in situ … La hibridación in situ es una técnica de laboratorio empleada para localizar … La hibridación in situ es una técnica de laboratorio empleada para localizar … La hibridación in situ es una técnica de laboratorio empleada para localizar …
Talking Glossary
Un gen de susceptibilidad al cáncer es un gen que, cuando cambia (o muta) confiere a la persona un mayor riesgo de desarrollar cáncer.
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
… Prostate Cancer … Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive … Cancer, Cell, Mitosis, Mutation … Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive …
News Release
NHGRI researchers have shown that areas of the genome related to brain development harbor variants that may account for behavioral differences among different dog lineages.
… how genomic variation can affect behavioral differences in humans. … Human Genome Research Institute (NHGRI) and published in the journal Cell , involved citizen science projects that … Ph.D., distinguished senior investigator and chief of the Cancer Genetics and Comparative Genomics Branch within …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… from over 10,000 tumors representing 33 types of cancer. … Francis S. Collins, M.D., Ph.D. "This analysis provides cancer researchers with unprecedented understanding of how, where and why tumors arise in humans, enabling better informed clinical trials and …
Fact Sheets
La hibridación fluorescente in situ brinda a los investigadores una manera de visualizar y mapear el material genético en las células de un individuo​.​ ​
… La hibridación fluorescente in situ (HFIS) brinda a los investigadores una manera de … hfis.jpg] ¿Qué es la HFIS? La hibridación fluorescente in situ (HFIS) brinda a los investigadores una manera de … Hibridación fluorescente in situ … La hibridación fluorescente in situ brinda a los investigadores una manera de visualizar …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
… will host a Town Hall at the University of Washington in Seattle, WA on June 19, 2018, and at Stanford University in Stanford, CA on July 17, 2018. …  After more than a decade, The Cancer Genome Atlas (TCGA) program is drawing to an end. A … National Cancer Institute (NCI), with over $300 million in total funding, TCGA has been hugely successful in its …
Staff
Dr. Heidi Parker is an Associate Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch, NHGRI.
… Dr. Heidi Parker is an associate Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch at the … to use the breed model to understand the history of dogs and canine variation. Dr. Parker applies genomic … into their elder years, they also develop many forms of cancer. Often in dogs these cancers show breed associated …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research … explore the entire spectrum of genomic changes involved in human cancer.  The project then molecularly characterized … in the most common type of lung cancer r  (2014)  TCGA bladder cancer study reveals potential drug targets, …