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Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… obvious cause - affects 1-2% of all children, accounting for about 40% of all hypertension diagnoses in children, and … Although a role for genetics in the development of the disease has been supported, it is unclear whether this …  Sickle cell disease (SCD) is one of the most common monogenetic diseases in the world, with high mortality …
The Informed Consent Resource
Explore the basic elements of informed consent that are required by the Common Rule and that are relevant to genomics.
… elements of informed consent that are required by the Common Rule (45 CFR 46, Subpart A) and that are relevant to … This Research Study Being Done? [Examples:] We are asking for your permission to collect samples and health information … how genes play a role in diseases such as cancer, heart disease, diabetes and glaucoma. [If applicable] The specific …
For Patients and Families
A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United States at any given time.
… A rare disease is generally considered to be a disease that affects … 25 million to 30 million Americans. … The exact cause for many rare diseases remains unknown. Still, for a significant portion, the problem can be traced to …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… give this lecture in the Sisters Chapel, a historic site for many reasons including being the place where the late Dr. … into how mosaicism at these sequences contributes to disease and inform the development of new genetic testing … enabling powerful genomics studies across institutes and centers.  “For more than 25 years, NISC has played an …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… methods as applied to mapping quantitative trait loci for obesity in model organisms. He contributed code to the R … influence the risk of developing Alzheimer or Parkinson disease, the two most common neurodegenerative diseases. Curriculum Vitae … …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… Complex Disease … A complex disease is caused by the interaction of … influences of the physical and social environment. For this reason, complex diseases are also called … is more directly caused by mutations in a single gene. Common examples of complex genetic diseases include heart …
Research Funding
Coordinates activities across the Genome Sequencing Program components
… and deposition; project completion Being a resource for logistics and communication among GSP program … including program webpages Developing specifications for common controls for rare variant association studies … … Tara Matise, Ph.D. and Steven Buyske, Ph.D. Funded Centers Centers for Common Disease Genomics Washington …
Staff
Dr. ​Adam Felsenfeld is a program director in the Division of Genome Sciences at the National Human Genome Research Institute.​
… Ph.D., is a Program Director with overall responsibility for the NHGRI Genome Sequencing Program (GSP), and specific responsibility for the NHGRI Centers for Common Disease Genomics program and the GSP Analysis Centers. …
Staff
Dr. Ayo Doumatey is a Research Fellow and Laboratory Manager at NHGRI's Center for Research on Genomics and Global Health.
… Dr. Doumatey is currently a Staff Scientist at the Center for Research on Genomics and Global Health (CRGGH), part of … The genomic landscape of African populations in health and disease. Hum Mol Genet. 2017 Oct 1;26(R2): R225-R236. doi: … with Normal Triglyceride Levels is the Most Common Lipid Pattern in West Africans and African Americans …
Research Funding
The centers study in innovative ways to address important ethical, legal, and social issues related to advances in genomics.
… is critical. All of these factors contribute to a need for new and more innovative approaches, including new … and funding mechanisms. The creation of research centers with the resources and expertise to design and … and Social Issues for Precision Medicine and Infectious Disease Gail Geller, Sc.D., $4 million (FY 2016-2019) This …