Search Results
News Release
As researchers uncover millions of DNA differences in genes, doctors struggle to know which of these inherited differences, called variants, really matter.
… As a growing number of medical centers and laboratories are sequencing patients' DNA, they continue to uncover millions of DNA differences in genes and the regions between the genes. But doctors have struggled to know which of these inherited differences - variants - really matter. …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… For the first time, National Institutes of Health (NIH) researchers have demonstrated in mice that gene therapy may be the best method for correcting the single … The gene therapy involved inserting a functional copy of the NPC1 gene into mice with the disease; the treated …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… National Institutes of Health researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted research on mice with a rare … the National Human Genome Research Institute (NHGRI), part of NIH, published their research in the Jan. 20, 2015, online …
News Release
Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from harmful DNA viruses, strengthening the plant's protections.
… Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from … use in many organisms, and this latest iteration develops gene-editing for use in plants. … plants' resistance to harmful viruses. Understanding plant genomics is valuable for human nutrition and health. In …
Fact Sheets
Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment.
… Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's … instructions needed to develop and direct the activities of nearly all living organisms. DNA molecules are made of two …
News Release
NIH researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), found that individuals diagnosed with ADHD had differences in genes that code for known chemicals that brain cells use to communicate.
… Researchers at the National Institutes of Health (NIH) have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder … NIH researchers unlock pattern of gene activity for ADHD … identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder …
Fact Sheet
Understanding gene therapy for sickle cell disease
… Presently, there are only a handful of options to manage or treat sickle cell disease. Now, researchers are developing new and emerging gene therapies to treat sickle cell disease. To help navigate … and individuals. This group met over the course of four workshops. …
Community Outreach
NHGRI is proud to help support the PBS documentary, “Ken Burns presents The Gene: An Intimate History,” based on the book by Siddhartha Mukherjee, M.D.
… help support the PBS documentary, “Ken Burns presents The Gene: An Intimate History,” based on the book by Siddhartha … a journey through key genetics discoveries that are some of the greatest achievements in the history of science. … In this fun animated series, the gene’s complex mechanisms are explored in simple ways. …
15 Ways Genomics Influences Our World
Advances in genomics are helping you access information about your genome from your home.
… Advances in genomics are helping you access information about your genome … them with information about their genome? Advances in genomics since the Human Genome Project have led to an … was valued at $117 million in 2017, suggesting millions of people are purchasing these tests. In contrast to clinical …
Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… Gene Therapy … Gene therapy is an experimental technique for treating … Genetic Disease, Genetic Disorder, Gene Mutation, Cancer Treatment, Healthcare … disorder. Often, gene therapy works by adding new copies of a gene that is broken, or by replacing a defective or …