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News Release
Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… Of DNA Elements (modENCODE) Consortium studied how gene expression patterns and regulatory proteins that help … genes and regulatory elements that control gene expression. The current work builds on initial catalogs … (or readouts) in a genome. They used large amounts of gene expression data generated in the ENCODE and modENCODE …
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… or off. … Deoxyribonucleic Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, Messenger RNA (mRNA), …
Staff
Dr. Elise Feingold is a scientific program manager in NHGRI's Division of Genome Sciences.
… 1992 as a program director focused on gene discovery, gene expression and functional genomics. Since 2019, Dr. Feingold … implications for the control of gamma-globin gene expression in man . Proc Natl Acad Sci U S A , … Excellence in Genomic Science (CEGS), gene discovery, gene expression, functional genomics … Dr. Elise Feingold is a …
Educational Resources
Translation is the process of translating the sequence of a messenger RNA (mRNA) molecule to a sequence of amino acids during protein synthesis.
… … Transcription, Base Pair, Cell, Cytoplasm, Gene, Gene Expression, Genetic Code, Messenger RNA (mRNA), Protein, …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… accessed through an NCBI Web site, called the Database of Genotype and Phenotype (dbGaP) located at: … … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene Variation, Personalized Medicine, Gene …
Educational Resources
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases.
… … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene Variation, Personalized Medicine, Gene …
Educational Resources
Transcription is the process of making an RNA copy of a gene sequence.
… … Cell, Cytoplasm, Deoxyribonucleic Acid (DNA), Gene, Gene Expression, Messenger RNA (mRNA), Nuclear Membrane, Nucleus, …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… of genes are expressed as messenger RNA in a particular tissue, and how a cell's regulatory networks control vast … fluorescent labels to complementary DNA (cDNA) from the tissue they are studying. The labeled cDNA binds to its … Human Genome Sequencing, Long-range Planning, Gene Expression, Sequence Variations, Phenotypes, Large-scale …
The Genomics Landscape
In the March 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the new fact sheets produced by the institute's Communications and Public Liaison Branch.
… in Psychiatric Disorders, Convergent Neuroscience, the Genotype-Tissue Expression  project, Human Pangenome Reference Consortium, …
The Genomics Landscape
In the February 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the December 2021 NHGRI symposium's success in confronting the difficult pasts of eugenics and scientific racism.
… Twitter account @NHGRI_Director .   All the best,   … The Genotype-Tissue Expression (GTEx) project generated NHGRI’s most frequently …