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Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… made novel findings regarding its role in hematopoietic stem cell production (Bresciani, Blood in press). Overall the … Liu PP. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by non-integrating plasmid …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… contains the instructions needed to build and maintain cells. These instructions are spelled out in the form of … when and where each gene is turned on or off in the cells and tissues of an organism. Depending on the technique … nearly every cell contains the same genes, but different cells show different patterns of gene expression. These …
Staff
Cynthia Tifft, M.D., Ph.D. is the deputy clinical director for the National Human Genome Research Institute.
… pathogenesis of LSDs, the Proia/Tifft team have generated induced pluripotent stem (iPS) cells from a patient with infantile Sandhoff …
Educational Resources
Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell's biochemical reactions.
Educational Resources
A centrosome is a cellular structure involved in the process of cell division.
… help separate the replicated chromosomes into the daughter cells. … A centrosome is a cellular structure involved in the …
Educational Resources
A nuclear membrane is a double membrane that encloses the cell nucleus.
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A nucleus is a membrane-bound organelle that contains the cell's chromosomes.
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A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.
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A fibroblast is the most common type of cell found in connective tissue.
Educational Resources
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent).
… Meiosis … Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of … that reduces the number of chromosomes in gametes (the sex cells, or egg and sperm). In humans, body (or somatic) cells …