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Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.
… population descriptors — race, ethnicity and genetic ancestry — which are often used to distinguish groups of … on the distinctions between race, ethnicity and genetic ancestry, and to advance the use of population descriptors in … ethnicity are not valid or reliable proxies for genetic ancestry. In addition, genetic ancestry is a poor proxy for …
News Release
Illumina will be developing a GWAS array based on data from the Human Heredity and Health in Africa Initiative.
… advance for those engaged in genomic research in African ancestry populations, Illumina will be developing a GWAS … in terms of trying to interrogate the genomes of African ancestry individuals with tools that were not designed to …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of Southern California** … Schaid Polygenic Risk of Disease in Populations of Diverse Ancestry UNC-Chapel Hill Yun Li*, Alexander Reiner, Nancy Cox … Across the Life-Span in Populations of Diverse Ancestry University of California, Los Angeles Bogdan …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… complex and intertwined relationships between a person's ancestry, ethnicity, and racial identity. So, we ask, is … cancer screenings, tried and true forensic techniques, DTC ancestry sleuthing, and COVID-19 tracking: all ways genomics … stories passed down through generations to taking genetic ancestry tests, we are compelled to know more about our …
Event
On December 7, 2022, NHGRI will host a webinar to discuss key findings from the Human Genetics and Genomics Workforce Survey Report.
… as U.S. citizens (73.3%) and their race, ethnicity or ancestry as white (67%). The top three primary areas of work … workforce demographics, which include race, ethnicity, ancestry; age; gender identity; sexual orientation; …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of … groups of people. The average percentage of African ancestry in the Americas varies widely: 87 percent in African … percent in Puerto Ricans, 7 percent in people with Mexican ancestry in Los Angeles and 4 percent in both Peruvians in …
News Release
NHGRI researchers collaborated with physicians and medical geneticists worldwide to create the Atlas of Human Malformation Syndromes in Diverse Populations.
… and descriptions of people with the same condition and ancestry. … Previously, the only available diagnostic atlas featured photos of patients with northern European ancestry, which often does not represent the characteristics … birth defects and genetic diseases in people of diverse ancestry." Congenital malformations , also known as birth …
Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… our risk locus. We are also applying trans- and local-ancestry admixture mapping models to other cohorts of … among genomic studies, with populations of African ancestry being particularly underrepresented, despite … using transcriptomics and genomics to describe the genetic ancestry and variation within African genomes and using the …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… of West Africans, African Americans and others of African ancestry carry a genomic variant that increases their risk of … on obesity to date have been in people of European ancestry, despite an increased risk of obesity in people of African ancestry. Obesity is a global health problem, contributing to …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… analyze your DNA and give information about your ancestry, kinship, lifestyle factors and potential disease … on the test, it may reveal some information about your ancestry and the health of you and your family. … One way … various areas, including medical decisions, food safety, ancestry and more.  … The DNA in a cell is not a single long …