Search Results
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of Southern California** … Schaid Polygenic Risk of Disease in Populations of Diverse Ancestry UNC-Chapel Hill Yun Li*, Alexander Reiner, Nancy Cox … Across the Life-Span in Populations of Diverse Ancestry University of California, Los Angeles Bogdan …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… complex and intertwined relationships between a person's ancestry, ethnicity, and racial identity. So, we ask, is … cancer screenings, tried and true forensic techniques, DTC ancestry sleuthing, and COVID-19 tracking: all ways genomics … stories passed down through generations to taking genetic ancestry tests, we are compelled to know more about our …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of … groups of people. The average percentage of African ancestry in the Americas varies widely: 87 percent in African … percent in Puerto Ricans, 7 percent in people with Mexican ancestry in Los Angeles and 4 percent in both Peruvians in …
News Release
NHGRI researchers collaborated with physicians and medical geneticists worldwide to create the Atlas of Human Malformation Syndromes in Diverse Populations.
… and descriptions of people with the same condition and ancestry. … Previously, the only available diagnostic atlas featured photos of patients with northern European ancestry, which often does not represent the characteristics … birth defects and genetic diseases in people of diverse ancestry." Congenital malformations , also known as birth …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… of West Africans, African Americans and others of African ancestry carry a genomic variant that increases their risk of … on obesity to date have been in people of European ancestry, despite an increased risk of obesity in people of African ancestry. Obesity is a global health problem, contributing to …
The Genomics Landscape
In the January 2025 issue of The Genomics Landscape, NHGRI Director Eric Green announces the appointment of Erin Ramos as the new director of the Division of Genome Sciences (DGSci).
… . All the best, … Mapping the relative accuracy of cross-ancestry prediction Lupi, et al. Nat. Comm. , Dec 2024, … participants in genomics studies have primarily European ancestry. The lack of representation of other ancestries … how the accuracy of PRSs varies across different ancestry groups. The researchers found that accuracy was …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… analyze your DNA and give information about your ancestry, kinship, lifestyle factors and potential disease … on the test, it may reveal some information about your ancestry and the health of you and your family. … One way … various areas, including medical decisions, food safety, ancestry and more. … The DNA in a cell is not a single long …
Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… our risk locus. We are also applying trans- and local-ancestry admixture mapping models to other cohorts of … using transcriptomics and genomics to describe the genetic ancestry and variation within African genomes and using the … exome sequencing reveals uncaptured variation and distinct ancestry in the Southern African population of Botswana. Am J …
Fact Sheet
Participation in genomics research is essential for improving the health of everyone.
… for their DNA to be used for research are from European ancestry, making many populations from across the globe … for genomics research have been overwhelmingly of European ancestry, which creates gaps in knowledge about the genomes … human DNA variation. The following graphic displays ancestry populations included in large-scale genomic studies …
Event
On November 5-9, 2024, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.  The annual meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics.Â
… islet cell depletion exacerbated in individuals of African ancestry with Type 2 diabetes 5169F Tam Tran Efficient large … Genetic Determinants of Liver Function Markers in African Ancestry Populations Speaker, Reagan Mogire 1:15 – 1:30 p.m. …