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- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Developmental Genotype-Tissue Expression (dGTEx)1
Educational Resources
The nucleolus is a region found within the cell nucleus that is concerned with producing and assembling the cell's ribosomes.
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… contains the instructions needed to build and maintain cells. These instructions are spelled out in the form of … when and where each gene is turned on or off in the cells and tissues of an organism. Depending on the technique … nearly every cell contains the same genes, but different cells show different patterns of gene expression. These …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… during leukemia development by microarray analysis with cells from Cbfb-MYH11 knock-in mice, and identified … mouse models. The zebrafish is a useful model for studying embryonic development and is easily amenable to large-scale … made novel findings regarding its role in hematopoietic stem cell production (Bresciani, Blood in press). Overall the …
Educational Resources
Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell's biochemical reactions.
Educational Resources
A centrosome is a cellular structure involved in the process of cell division.
… help separate the replicated chromosomes into the daughter cells. … A centrosome is a cellular structure involved in the …
Educational Resources
A nuclear membrane is a double membrane that encloses the cell nucleus.
Educational Resources
A nucleus is a membrane-bound organelle that contains the cell's chromosomes.
Educational Resources
A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.
Educational Resources
A fibroblast is the most common type of cell found in connective tissue.
Educational Resources
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent).
… Meiosis … Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of … that reduces the number of chromosomes in gametes (the sex cells, or egg and sperm). In humans, body (or somatic) cells …