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Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… the person makes in response to the vaccine can cause an immune response without a person ever having been exposed to … Later, if the person is exposed to the virus, their immune system will recognize the virus and respond to it.  …
News Release
Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from harmful DNA viruses, strengthening the plant's protections.
… protect plants from harmful DNA viruses. The CRISPR/Cas9 system has previously been adapted for use in many organisms, … scientists inserted the code for an ancient bacterial immune system into a plant's genome to successfully strengthen the …
Clinical Research
NHGRI researchers work with patients and families to explore how genes cause or influence diseases, and develop more effective diagnostics and treatments.
… Disorders Healthy Individuals Genetic Analysis of Immune Disorders Healthy Individuals PET Scanning in … Immunologic Deficiency Syndrome Genetic Analysis of Immune Disorders Immunologic Deficiency Syndrome Molecular … into Ciliopathies Job's Syndrome Genetic Analysis of Immune Disorders Joubert Syndrome Clinical and Molecular …
News Release
NHGRI researchers investigated the Behcet's disease using Illumina's Immunochip.
… with disease susceptibility, many of which are involved in immune response to invading pathogens. The study - Dense genotyping of immune-related loci implicates host responses to microbial … of Nature Genetics . Related Resources Dense genotyping of immune-related loci implicates host responses to microbial …
Fact Sheet
Learn about the different types of hemoglobin.
… bone marrow . White blood cells are part of the body's immune system; they help the body fight infection and other …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… pathways in different systems in the body, such as skin, immune cells and lung. The resulting insights into the … pathways in different systems of the body, such as skin, immune cells and lung. Credit: Darryl Leja, NHGRI. Over the … Ph.D. and Alexander Rudensky, Ph.D. The body's immune system can cause inflammation, which plays a central role in …
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… the interplay between mitochondrial metabolism and the immune system. His NIH Clinical Center protocols, the NIH MINI Study , is the first organized effort to study immune function in patients with disorders of mitochondrial …
Fact Sheet
Early in the COVID-19 pandemic, researchers used state-of-the-art genomic sequencers to quickly sequence the SARS-CoV-2 virus.
… thereby making it an effective antigen, or target for the immune system to recognize and attack. The genetic sequence is then …
Fact Sheet
Ribonucleic acid (RNA) is an essential molecule that performs many roles in the cell, from carrying the instructions to make proteins to regulating genes.
… mRNAs to produce virus proteins and display them to the immune system. This teaches the immune system to recognize the virus, promoting a strong …
NEWS RELEASE
Final outcomes from the most comprehensive analysis to-date of humans and their microbiomes definitively link microbes and microbial activities with health problems.
… the healthy birth of an infant, the iHMP’s first model system, the Vaginal Microbiome Consortium Multi-Omic … in the gut microbiome. "Each individual's microbiome and immune system clearly responded in a distinct, coordinated … when a person has respiratory viral infections, their immune system is activated to fight the infection. …