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TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Steven Benowitz … Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number of new … about the biology and development of a rare form of kidney cancer. … They found that the disease - chromophobe renal … of the 66 ChRCC tumors studied, a high number for a rare cancer. The study revealed increased numbers of mitochondria …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… genomic research for NHGRI investigators. As head of the Cancer Genomics Unit, his research efforts led to the … to study the molecular pathogenesis in FA. … The Cancer Genomics Unit (CGU) focuses on adopting genomic … in search of the gene responsible for early onset breast cancer ( BRCA1 ), CGU developed resources and aided in the …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… is a leader in the application of genome science to cancer research. His recent studies investigate the genetic … Asian Hepatocellular Carcinoma and Cholangiocarcinoma . Cancer Cell , 32(1):57-70.e3. 2017. Killian JK, Dorssers LC, … osteosarcoma profiling, melanoma profiling, breast cancer profiling, technology development … Paul Meltzer, …
Staff
Dr. Heidi Parker is an Associate Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch, NHGRI.
… Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch at the … clusters and shared regions of dysregulation with human bladder tumors . BMC Cancer 24;20(1):251, 2020. Parker HG*, … human BRAF V600E Is common in naturally occurring canine bladder cancer -Evidence for a relevant model system and …
… Cáncer de próstata … Prostate cancer is a disease characterized by uncontrolled cell growth … which is part of the male reproductive system. Prostate cancer generally affects men over the age of 50. It is responsible for more deaths among men than any other cancer except lung cancer. …
Talking Glossary
Un carcinógeno es una sustancia, organismo o agente capaz de causar cáncer.
… is a substance, organism or agent capable of causing cancer. Carcinogens may occur naturally in the environment …
Talking Glossary
BRCA1 y BRCA2 son los dos primeros genes que se identificaron como asociados a tipos hereditarios del cáncer de mama y de ovario. Las personas con mutaciones en BRCA1 o BRCA2 tienen un riesgo mucho más alto de desarrollar cáncer de mama, de ovario u otros tipos de cáncer en comparación con las personas que no tienen mutaciones en estos genes.
… found to be associated with inherited forms of breast cancer and ovarian cancer. People with mutations in either BRCA1 or BRCA2 have a … risk for developing breast, ovarian or other types of cancer than those without mutations in the genes. Both BRCA1 …
Talking Glossary
Un oncogén es un gen que sufrió una mutación y que tiene el potencial de causar cáncer.
… oncogene is a mutated gene that has the potential to cause cancer. Before an oncogene becomes mutated, it is called a … and it plays a role in regulating normal cell division. Cancer can arise when a proto-oncogene is mutated, changing …
Clinical Studies
The IDENTIFY Study is a study exploring how prenatal blood test results for the baby might also detect cancer in the mother.
… asymptomatic person.   I’ve already been diagnosed with cancer. Can I still participate? Yes. If you were diagnosed with cancer after receiving an abnormal or non-reportable NIPT … participants for up to 5 years. If you are diagnosed with cancer, we will collect information from you, but you will …
News Release
NHGRI researchers have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.
… to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. Since 2012, Laura Koehly, Ph.D., and her research … trees associated with heart disease, diabetes, breast cancer and colorectal cancer. Definitions of each disease and …