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- Ethical, Legal and Social Implications (ELSI) Research Program1
- Genomics-Enabled Learning Health Systems (gLHS)1
- Genome Technology Program3
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Developmental Genotype-Tissue Expression (dGTEx)1
Educational Resources
A nucleus is a membrane-bound organelle that contains the cell's chromosomes.
… A nucleus is a membrane-bound organelle that contains the cell's chromosomes. … Chromosome, Cell, Deoxyribonucleic Acid (DNA) … A nucleus, as related to genomics, is the membrane-enclosed organelle within a cell that contains the chromosomes. An array of holes, or …
Educational Resources
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent).
… set from each parent). … Meiosis, Sexually Reproduction, Cell Biology, Chromosome … Meiosis is a type of cell division in sexually reproducing organisms that reduces … that unite during fertilization must be haploid, with a single set of chromosomes. During meiosis, each diploid cell …
Educational Resources
A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.
… Body … A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and … especially proteins destined to be exported from the cell. … Golgi Apparatus, Camillo Golgi, Cell Biology … A Golgi body, also known as a Golgi apparatus, …
Educational Resources
A fibroblast is the most common type of cell found in connective tissue.
… Fibroblast … A fibroblast is the most common type of cell found in connective tissue. … Cell Biology, Wound Healing … A fibroblast is a type of cell that contributes to the formation of connective tissue, …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… cancer. … They found that the disease - chromophobe renal cell carcinoma (ChRCC) - stems in part from alterations in genes in the mitochondria, the cell's energy supplier. They also discovered that the tumor … North Carolina, Chapel Hill, performed a complex array of analyses, including examining the entire genomes of 50 of the …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to … Mitochondria are important components of nearly every cell in the body because they convert food and oxygen into … affect the immune system. Using a genomic technique called single-cell RNA sequencing, which analyzes gene activity in …
Educational Resources
Metaphase is a stage during the process of cell division (mitosis or meiosis).
… Metaphase … Metaphase is a stage during the process of cell division (mitosis or meiosis). … Metaphase, Genetic Material, Cell Biology, Chromosome … Metaphase is a stage during the process of cell division (mitosis or meiosis). Normally, individual …
News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
… to 3 million people have a gene variant associated sickle cell trait (SCT) and most never have related health … risk for some individuals." Hematologists and sickle cell experts evaluated the association of SCT with 24 health … said Gregory Kato, M.D., director of the Adult Sickle Cell Center of Excellence at the University of Pittsburgh …
Educational Resources
Proteins are an important class of molecules found in all living cells.
… important class of molecules found in all living cells. … Cell, Gene Amplification, Amino Acids, Gene … Proteins are …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
… is a group of diseases characterized by uncontrolled cell growth. … Cancer, Cell Division, Mutation, DNA Error, Metastasis, Tumor, Family … are many different types of cancer, and each begins when a single cell acquires a genomic change (or mutation) that …