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News Release
Researchers funded by NHGRI’s Genome Technology Program include a wide range of investigators with a variety of scientific expertise.
… looking at the expression of a few select genes in a whole tissue or looking at more genes in cells grown in an … gene expression and understand genome function at the tissue level. To do this, the researchers built an array of … gene expression of many genes in the context of the whole tissue,” says Dr. Chen. Already, the group has applied their …
The Genomics Landscape
In the December 2024 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the keynote speaker at the institute's annual symposium, Kate Rubins, a biologist and NASA astronaut who was the first person to sequence DNA in space.
… to the epigenome. However, after examining post-mortem tissue of people with ADHD, the researchers found no …
News Release
Researchers have found powerful clues to why certain processes and systems in the mouse are so different from those in people.
… researchers found that differences appeared in specific tissue and cell types. "We didn't know before these results … sites (which identify regulatory DNA) in 45 mouse cell and tissue types to those in humans. They reported in Science … his colleagues compared gene expression in 15 different tissue types in mice and humans. Contrary to previous …
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
… to an immune-system receptor. S. epidermidis also inhibits tissue colonization by the highly pathogenic S. aureus , the … Among these functions are overall immune system screening, tissue repair, wound healing, inflammation control, … If S. epidermidis fails to confine S. aureus to the nasal tissue that it often inhabits, the human host could be in for …
Educational Resources
Proteins are an important class of molecules found in all living cells.
Talking Glossary
RNA-seq, short for RNA sequencing, is a method for sequencing an entire set of RNA molecules.
… This method involves isolating RNA molecules in the tissue or cell sample, copying those RNAs into DNA and then …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… the researchers looked at was the cerebriform connective tissue nevus (CCTN), which is a disfiguring, massive …
Staff
Dr. Alexander Arguello is a program director in the NHGRI Division of Genome Sciences.
… Reference Program (HGRP) and Developmental Genotype-Tissue Expression (dGTEx) initiatives as well as the …
Staff
Dr. Michael Erdos is an Associate Investigator in the Molecular Genetics Section of the Center for Precision Health Research.
… of T2D. Dr. Erdos is the lead scientist in the FUSION tissue biopsy project which aims to investigate tissue specific effects of T2D associated variants on the … Dr. Erdos has been collecting pancreatic islets and liver tissue from cadaveric tissue distribution organizations in …
The Informed Consent Resource
Explore the basic elements of informed consent that are required by the Common Rule and that are relevant to genomics.
… name of previous project or biobank]. Your blood and tissue samples contain DNA, which makes up the genes that … The process for the collection of samples (blood or other tissue) and health information. Whether researchers will have … If your doctors collected a blood sample (or other tissue sample) as part of your medical care, we will study …